Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer’s disease
Identifieur interne : 000D36 ( Main/Exploration ); précédent : 000D35; suivant : 000D37Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer’s disease
Auteurs : Jean-Charles Lambert [France] ; Carla A. Ibrahim-Verbaas [Pays-Bas] ; Denise Harold [Royaume-Uni] ; Adam C. Naj [États-Unis] ; Rebecca Sims [Royaume-Uni] ; Céline Bellenguez [France] ; Gyungah Jun [États-Unis] ; Anita L. Destefano [États-Unis] ; Joshua C. Bis [États-Unis] ; Gary W. Beecham [États-Unis] ; Benjamin Grenier-Boley [France] ; Giancarlo Russo [Suisse] ; Tricia A. Thornton-Wells [États-Unis] ; Nicola Jones [Royaume-Uni] ; Albert V. Smith [Islande] ; Vincent Chouraki [France] ; Charlene Thomas [Royaume-Uni] ; M Arfan Ikram [Pays-Bas] ; Diana Zelenika [France] ; Badri N. Vardarajan [États-Unis] ; Yoichiro Kamatani [France] ; Chiao-Feng Lin [États-Unis] ; Amy Gerrish [Royaume-Uni] ; Helena Schmidt [Autriche] ; Brian Kunkle [États-Unis] ; Melanie L. Dunstan [Royaume-Uni] ; Agustin Ruiz [Espagne] ; Marie-Thérèse Bihoreau [France] ; Seung-Hoan Choi [États-Unis] ; Christiane Reitz [États-Unis] ; Florence Pasquier [France] ; Paul Hollingworth [Royaume-Uni] ; Alfredo Ramirez [Allemagne] ; Olivier Hanon [France] ; Annette L. Fitzpatrick [États-Unis] ; Joseph D. Buxbaum [États-Unis] ; Dominique Campion [France] ; Paul K. Crane [États-Unis] ; Clinton Baldwin [États-Unis] ; Tim Becker [Allemagne] ; Vilmundur Gudnason [Islande] ; Carlos Cruchaga [États-Unis] ; David Craig [Royaume-Uni] ; Najaf Amin [Pays-Bas] ; Claudine Berr [France] ; Oscar L. Lopez [États-Unis] ; Philip L. De Jager [États-Unis] ; Vincent Deramecourt [France] ; Janet A. Johnston [Royaume-Uni] ; Denis Evans [États-Unis] ; Simon Lovestone [Royaume-Uni] ; Luc Letenneur [France] ; Francisco J. Mor N [Espagne] ; David C. Rubinsztein [Royaume-Uni] ; Gudny Eiriksdottir [Islande] ; Kristel Sleegers [Belgique] ; Alison M. Goate [États-Unis] ; Nathalie Fiévet [France] ; Matthew J. Huentelman [États-Unis] ; Michael Gill [Irlande (pays)] ; Kristelle Brown [Royaume-Uni] ; M Ilyas Kamboh [États-Unis] ; Lina Keller [Suède] ; Pascale Barberger-Gateau [France] ; Bernadette Mcguinness [Royaume-Uni] ; Eric B. Larson [États-Unis] ; Robert Green [États-Unis] ; Amanda J. Myers [États-Unis] ; Carole Dufouil [France] ; Stephen Todd [Royaume-Uni] ; David Wallon [France] ; Seth Love [Royaume-Uni] ; Ekaterina Rogaeva [Canada] ; John Gallacher [Royaume-Uni] ; Peter St George-Hyslop [Royaume-Uni, Canada] ; Jordi Clarimon [Espagne] ; Alberto Lleo [Espagne] ; Anthony Bayer [Royaume-Uni] ; Debby W. Tsuang [États-Unis] ; Lei Yu [États-Unis] ; Magda Tsolaki [Grèce] ; Paola Bossù [Italie] ; Gianfranco Spalletta [Italie] ; Petroula Proitsi [Royaume-Uni] ; John Collinge [Royaume-Uni] ; Sandro Sorbi [Italie] ; Florentino Sanchez-Garcia [Espagne] ; Nick C. Fox [Royaume-Uni] ; John Hardy [Royaume-Uni] ; Maria Candida Deniz Naranjo [Espagne] ; Paolo Bosco [Italie] ; Robert Clarke [Royaume-Uni] ; Carol Brayne [Royaume-Uni] ; Daniela Galimberti [Italie] ; Michelangelo Mancuso [Italie] ; Fiona Matthews [Royaume-Uni] ; Susanne Moebus [Allemagne] ; Patrizia Mecocci [Italie] ; Maria Del Zompo [Italie] ; Wolfgang Maier [Allemagne] ; Harald Hampel [Allemagne] ; Alberto Pilotto [Italie] ; Maria Bullido [Espagne] ; Francesco Panza [Italie] ; Paolo Caffarra [Italie] ; Benedetta Nacmias [Italie] ; John R. Gilbert [États-Unis] ; Manuel Mayhaus [Allemagne] ; Lars Lannfelt [Suède] ; Hakon Hakonarson [États-Unis] ; Sabrina Pichler [Allemagne] ; Minerva M. Carrasquillo [États-Unis] ; Martin Ingelsson [Suède] ; Duane Beekly [États-Unis] ; Victoria Alvarez [Espagne] ; Fanggeng Zou [États-Unis] ; Otto Valladares [États-Unis] ; Steven G. Younkin [États-Unis] ; Eliecer Coto [Espagne] ; Kara L. Hamilton-Nelson [États-Unis] ; Wei Gu [Allemagne] ; Cristina Razquin [Espagne] ; Pau Pastor [Espagne] ; Ignacio Mateo [Espagne] ; Michael J. Owen [Royaume-Uni] ; Kelley M. Faber [États-Unis] ; Palmi V. Jonsson [Islande] ; Onofre Combarros [Espagne] ; Michael C. O Onovan [Royaume-Uni] ; Laura B. Cantwell [États-Unis] ; Hilkka Soininen [Finlande] ; Deborah Blacker [États-Unis] ; Simon Mead [Royaume-Uni] ; Thomas H. Mosley [États-Unis] ; David A. Bennett [États-Unis] ; Tamara B. Harris [États-Unis] ; Laura Fratiglioni [Suède] ; Clive Holmes [Royaume-Uni] ; Renee F A G. De Bruijn [Pays-Bas] ; Peter Passmore [Royaume-Uni] ; Thomas J. Montine [États-Unis] ; Karolien Bettens [Belgique] ; Jerome I. Rotter [États-Unis] ; Alexis Brice [France] ; Kevin Morgan [Royaume-Uni] ; Tatiana M. Foroud [États-Unis] ; Walter A. Kukull [États-Unis] ; Didier Hannequin [France] ; John F. Powell [Royaume-Uni] ; Michael A. Nalls [États-Unis] ; Karen Ritchie [France, Royaume-Uni] ; Kathryn L. Lunetta [États-Unis] ; John S K. Kauwe [États-Unis] ; Eric Boerwinkle [États-Unis] ; Matthias Riemenschneider [Allemagne] ; Mercè Boada [Espagne] ; Mikko Hiltunen [Finlande] ; Eden R. Martin [États-Unis] ; Reinhold Schmidt [Autriche] ; Dan Rujescu [Allemagne] ; Li-San Wang [États-Unis] ; Jean-François Dartigues [France] ; Richard Mayeux [États-Unis] ; Christophe Tzourio [France] ; Albert Hofman [Pays-Bas] ; Markus M. Nöthen [Allemagne] ; Caroline Graff [États-Unis, Suède] ; Bruce M. Psaty [États-Unis] ; Lesley Jones [Royaume-Uni] ; Jonathan L. Haines [États-Unis] ; Peter A. Holmans [Royaume-Uni] ; Mark Lathrop [France, Canada] ; Margaret A. Pericak-Vance [États-Unis] ; Lenore J. Launer [États-Unis] ; Lindsay A. Farrer [États-Unis] ; Cornelia M. Van Duijn [Pays-Bas] ; Christine Van Broeckhoven [Belgique] ; Valentina Moskvina [Royaume-Uni] ; Sudha Seshadri [États-Unis] ; Julie Williams [Royaume-Uni] ; Gerard D. Schellenberg [États-Unis] ; Philippe Amouyel [France]Source :
- Nature genetics [ 1061-4036 ] ; 2013.
Abstract
Eleven susceptibility loci for late-onset Alzheimer’s disease (LOAD) were identified by previous studies; however, a large portion of the genetic risk for this disease remains unexplained. We conducted a large, two-stage meta-analysis of genome-wide association studies (GWAS) in individuals of European ancestry. In stage 1, we used genotyped and imputed data (7,055,881 SNPs) to perform meta-analysis on 4 previously published GWAS data sets consisting of 17,008 Alzheimer’s disease cases and 37,154 controls. In stage 2,11,632 SNPs were genotyped and tested for association in an independent set of 8,572 Alzheimer’s disease cases and 11,312 controls. In addition to the
Url:
DOI: 10.1038/ng.2802
PubMed: 24162737
PubMed Central: 3896259
Affiliations:
- Allemagne, Autriche, Belgique, Canada, Espagne, Finlande, France, Grèce, Irlande (pays), Islande, Italie, Pays-Bas, Royaume-Uni, Suisse, Suède, États-Unis
- Angleterre, Angleterre de l'Est, Aquitaine, Arizona, Bavière, Californie, Canton de Zurich, Catalogne, Communauté de Madrid, District de Cologne, District de Darmstadt, District de Haute-Bavière, East Middle Sweden, Floride, Grand Londres, Haute-Normandie, Hauts-de-France, Hesse (Land), Hollande-Méridionale, Illinois, Indiana, Languedoc-Roussillon, Latium, Lombardie, Maryland, Massachusetts, Missouri (État), Nord-Pas-de-Calais, Nottinghamshire, Nouvelle-Aquitaine, Occitanie (région administrative), Ontario, Oxfordshire, Pennsylvanie, Province d'Anvers, Rhénanie-du-Nord-Westphalie, Région Normandie, Région flamande, Svealand, Tennessee, Texas, Toscane, Utah, Washington (État), État de New York, État du Mississippi, Île-de-France
- Anvers, Barcelone, Bonn, Bordeaux, Cambridge, Francfort-sur-le-Main, Leyde, Lille, Londres, Madrid, Milan, Montpellier, Munich, New York, Nottingham, Oxford, Paris, Pise, Pittsburgh, Rome, Rotterdam, Rouen, Saint-Louis (Missouri), Seattle, Stockholm, Toronto, Uppsala, Zurich, Évry (Essonne)
- Université Columbia, Université Lille 2, Université Louis-et-Maximilien de Munich, Université Pierre-et-Marie-Curie, Université autonome de Barcelone, Université autonome de Madrid, Université d'Anvers, Université d'Oxford, Université d'Uppsala, Université de Cambridge, Université de Nottingham, Université de Pise, Université de Pittsburgh, Université de Toronto, Université de Washington, Université de Zurich, École de médecine (Université Washington de Saint-Louis)
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Le document en format XML
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Destefano</name><affiliation wicri:level="2"><nlm:aff id="A11">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Bis, Joshua C" sort="Bis, Joshua C" uniqKey="Bis J" first="Joshua C" last="Bis">Joshua C. Bis</name><affiliation wicri:level="4"><nlm:aff id="A12">Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Beecham, Gary W" sort="Beecham, Gary W" uniqKey="Beecham G" first="Gary W" last="Beecham">Gary W. Beecham</name><affiliation wicri:level="2"><nlm:aff id="A13">John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A14">Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Grenier Boley, Benjamin" sort="Grenier Boley, Benjamin" uniqKey="Grenier Boley B" first="Benjamin" last="Grenier-Boley">Benjamin Grenier-Boley</name><affiliation wicri:level="3"><nlm:aff id="A1">INSERM, U744, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U744, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A2">Université Lille 2, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Université Lille 2, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement><settlement type="city">Lille</settlement></placeName><orgName type="university">Université Lille 2</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A3">Institut Pasteur de Lille, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur de Lille, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Russo, Giancarlo" sort="Russo, Giancarlo" uniqKey="Russo G" first="Giancarlo" last="Russo">Giancarlo Russo</name><affiliation wicri:level="4"><nlm:aff id="A15">Functional Genomics Center Zurich, Eidgenössische Technische Hochschule (ETH)/University of Zurich, Zurich, Switzerland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suisse</country><wicri:regionArea>Functional Genomics Center Zurich, Eidgenössische Technische Hochschule (ETH)/University of Zurich, Zurich</wicri:regionArea><orgName type="university">Université de Zurich</orgName><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region></placeName></affiliation></author><author><name sortKey="Thornton Wells, Tricia A" sort="Thornton Wells, Tricia A" uniqKey="Thornton Wells T" first="Tricia A" last="Thornton-Wells">Tricia A. Thornton-Wells</name><affiliation wicri:level="2"><nlm:aff id="A16">Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Jones, Nicola" sort="Jones, Nicola" uniqKey="Jones N" first="Nicola" last="Jones">Nicola Jones</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Smith, Albert V" sort="Smith, Albert V" uniqKey="Smith A" first="Albert V" last="Smith">Albert V. Smith</name><affiliation wicri:level="1"><nlm:aff id="A17">Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A18">Icelandic Heart Association, Kopavogur, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation></author><author><name sortKey="Chouraki, Vincent" sort="Chouraki, Vincent" uniqKey="Chouraki V" first="Vincent" last="Chouraki">Vincent Chouraki</name><affiliation wicri:level="3"><nlm:aff id="A1">INSERM, U744, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U744, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A2">Université Lille 2, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Université Lille 2, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement><settlement type="city">Lille</settlement></placeName><orgName type="university">Université Lille 2</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A3">Institut Pasteur de Lille, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur de Lille, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Thomas, Charlene" sort="Thomas, Charlene" uniqKey="Thomas C" first="Charlene" last="Thomas">Charlene Thomas</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Ikram, M Arfan" sort="Ikram, M Arfan" uniqKey="Ikram M" first="M Arfan" last="Ikram">M Arfan Ikram</name><affiliation wicri:level="3"><nlm:aff id="A4">Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Neurology, Erasmus MC University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A19">Department of Radiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Radiology, Erasmus MC University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A20">Netherlands Consortium for Healthy Aging, Leiden, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherlands Consortium for Healthy Aging, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Zelenika, Diana" sort="Zelenika, Diana" uniqKey="Zelenika D" first="Diana" last="Zelenika">Diana Zelenika</name><affiliation wicri:level="3"><nlm:aff id="A21">Centre National de Génotypage, Institut Génomique, Commissariat à l’Energie Atomique, Evry, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre National de Génotypage, Institut Génomique, Commissariat à l’Energie Atomique, Evry</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Évry (Essonne)</settlement></placeName></affiliation></author><author><name sortKey="Vardarajan, Badri N" sort="Vardarajan, Badri N" uniqKey="Vardarajan B" first="Badri N" last="Vardarajan">Badri N. Vardarajan</name><affiliation wicri:level="2"><nlm:aff id="A9">Department of Medicine (Biomedical Genetics), Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine (Biomedical Genetics), Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Kamatani, Yoichiro" sort="Kamatani, Yoichiro" uniqKey="Kamatani Y" first="Yoichiro" last="Kamatani">Yoichiro Kamatani</name><affiliation wicri:level="3"><nlm:aff id="A22">Fondation Jean Dausset, Centre d’Etude du Polymorphisme Humain (CEPH), Paris, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Fondation Jean Dausset, Centre d’Etude du Polymorphisme Humain (CEPH), Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Lin, Chiao Feng" sort="Lin, Chiao Feng" uniqKey="Lin C" first="Chiao-Feng" last="Lin">Chiao-Feng Lin</name><affiliation wicri:level="2"><nlm:aff id="A23">Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Gerrish, Amy" sort="Gerrish, Amy" uniqKey="Gerrish A" first="Amy" last="Gerrish">Amy Gerrish</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Schmidt, Helena" sort="Schmidt, Helena" uniqKey="Schmidt H" first="Helena" last="Schmidt">Helena Schmidt</name><affiliation wicri:level="1"><nlm:aff id="A24">Institute for Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Autriche</country><wicri:regionArea>Institute for Molecular Biology and Biochemistry, Medical University of Graz, Graz</wicri:regionArea><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Kunkle, Brian" sort="Kunkle, Brian" uniqKey="Kunkle B" first="Brian" last="Kunkle">Brian Kunkle</name><affiliation wicri:level="2"><nlm:aff id="A13">John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Dunstan, Melanie L" sort="Dunstan, Melanie L" uniqKey="Dunstan M" first="Melanie L" last="Dunstan">Melanie L. Dunstan</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Ruiz, Agustin" sort="Ruiz, Agustin" uniqKey="Ruiz A" first="Agustin" last="Ruiz">Agustin Ruiz</name><affiliation wicri:level="3"><nlm:aff id="A25">Memory Clinic of Fundació Alzheimer Centre Educacional (ACE). Institut Català de Neurociències Aplicades, Barcelona, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Memory Clinic of Fundació Alzheimer Centre Educacional (ACE). Institut Català de Neurociències Aplicades, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Bihoreau, Marie Therese" sort="Bihoreau, Marie Therese" uniqKey="Bihoreau M" first="Marie-Thérèse" last="Bihoreau">Marie-Thérèse Bihoreau</name><affiliation wicri:level="3"><nlm:aff id="A21">Centre National de Génotypage, Institut Génomique, Commissariat à l’Energie Atomique, Evry, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre National de Génotypage, Institut Génomique, Commissariat à l’Energie Atomique, Evry</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Évry (Essonne)</settlement></placeName></affiliation></author><author><name sortKey="Choi, Seung Hoan" sort="Choi, Seung Hoan" uniqKey="Choi S" first="Seung-Hoan" last="Choi">Seung-Hoan Choi</name><affiliation wicri:level="2"><nlm:aff id="A11">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Reitz, Christiane" sort="Reitz, Christiane" uniqKey="Reitz C" first="Christiane" last="Reitz">Christiane Reitz</name><affiliation wicri:level="4"><nlm:aff id="A26">Taub Institute on Alzheimer’s Disease and the Aging Brain, Department of Neurology, Columbia University, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Taub Institute on Alzheimer’s Disease and the Aging Brain, Department of Neurology, Columbia University, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A27">Gertrude H. Sergievsky Center, Department of Neurology, Columbia University, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Gertrude H. Sergievsky Center, Department of Neurology, Columbia University, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Pasquier, Florence" sort="Pasquier, Florence" uniqKey="Pasquier F" first="Florence" last="Pasquier">Florence Pasquier</name><affiliation wicri:level="4"><nlm:aff id="A2">Université Lille 2, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Université Lille 2, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement><settlement type="city">Lille</settlement></placeName><orgName type="university">Université Lille 2</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A28">Centre National de Reference pour les Malades Alzheimer Jeunes (CNR-MAJ), Centre Hospitalier Régional Universitaire de Lille, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre National de Reference pour les Malades Alzheimer Jeunes (CNR-MAJ), Centre Hospitalier Régional Universitaire de Lille, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Hollingworth, Paul" sort="Hollingworth, Paul" uniqKey="Hollingworth P" first="Paul" last="Hollingworth">Paul Hollingworth</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Ramirez, Alfredo" sort="Ramirez, Alfredo" uniqKey="Ramirez A" first="Alfredo" last="Ramirez">Alfredo Ramirez</name><affiliation wicri:level="3"><nlm:aff id="A29">Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Psychiatry and Psychotherapy, University of Bonn, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A30">Institute of Human Genetics, University of Bonn, Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Human Genetics, University of Bonn, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation></author><author><name sortKey="Hanon, Olivier" sort="Hanon, Olivier" uniqKey="Hanon O" first="Olivier" last="Hanon">Olivier Hanon</name><affiliation wicri:level="3"><nlm:aff id="A31">University Paris Descartes, Sorbonne Paris V, Broca Hospital, Geriatrics Department, Paris, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>University Paris Descartes, Sorbonne Paris V, Broca Hospital, Geriatrics Department, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Fitzpatrick, Annette L" sort="Fitzpatrick, Annette L" uniqKey="Fitzpatrick A" first="Annette L" last="Fitzpatrick">Annette L. Fitzpatrick</name><affiliation wicri:level="4"><nlm:aff id="A12">Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A32">Department of Epidemiology, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A33">Department of Global Health, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Global Health, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Buxbaum, Joseph D" sort="Buxbaum, Joseph D" uniqKey="Buxbaum J" first="Joseph D" last="Buxbaum">Joseph D. Buxbaum</name><affiliation wicri:level="2"><nlm:aff id="A34">Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Neuroscience, Mount Sinai School of Medicine, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A35">Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Psychiatry, Mount Sinai School of Medicine, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A36">Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Campion, Dominique" sort="Campion, Dominique" uniqKey="Campion D" first="Dominique" last="Campion">Dominique Campion</name><affiliation wicri:level="3"><nlm:aff id="A37">CNR-MAJ, INSERM, U1079, Rouen University Hospital, Rouen, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNR-MAJ, INSERM, U1079, Rouen University Hospital, Rouen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Haute-Normandie</region><settlement type="city">Rouen</settlement></placeName></affiliation></author><author><name sortKey="Crane, Paul K" sort="Crane, Paul K" uniqKey="Crane P" first="Paul K" last="Crane">Paul K. Crane</name><affiliation wicri:level="4"><nlm:aff id="A38">Department of Medicine, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Baldwin, Clinton" sort="Baldwin, Clinton" uniqKey="Baldwin C" first="Clinton" last="Baldwin">Clinton Baldwin</name><affiliation wicri:level="2"><nlm:aff id="A9">Department of Medicine (Biomedical Genetics), Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine (Biomedical Genetics), Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Becker, Tim" sort="Becker, Tim" uniqKey="Becker T" first="Tim" last="Becker">Tim Becker</name><affiliation wicri:level="3"><nlm:aff id="A39">German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>German Center for Neurodegenerative Diseases (DZNE), Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A40">Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation wicri:level="1"><nlm:aff id="A17">Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A18">Icelandic Heart Association, Kopavogur, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation></author><author><name sortKey="Cruchaga, Carlos" sort="Cruchaga, Carlos" uniqKey="Cruchaga C" first="Carlos" last="Cruchaga">Carlos Cruchaga</name><affiliation wicri:level="4"><nlm:aff id="A41">Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A42">Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, Missouri, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation></author><author><name sortKey="Craig, David" sort="Craig, David" uniqKey="Craig D" first="David" last="Craig">David Craig</name><affiliation wicri:level="1"><nlm:aff id="A43">Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast</wicri:regionArea><wicri:noRegion>Belfast</wicri:noRegion></affiliation></author><author><name sortKey="Amin, Najaf" sort="Amin, Najaf" uniqKey="Amin N" first="Najaf" last="Amin">Najaf Amin</name><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Berr, Claudine" sort="Berr, Claudine" uniqKey="Berr C" first="Claudine" last="Berr">Claudine Berr</name><affiliation wicri:level="3"><nlm:aff id="A44">INSERM, U1061, Faculty of Medicine, Hôpital La Colombière, Montpellier, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U1061, Faculty of Medicine, Hôpital La Colombière, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Lopez, Oscar L" sort="Lopez, Oscar L" uniqKey="Lopez O" first="Oscar L" last="Lopez">Oscar L. Lopez</name><affiliation wicri:level="2"><nlm:aff id="A45">Departments of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Departments of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="De Jager, Philip L" sort="De Jager, Philip L" uniqKey="De Jager P" first="Philip L" last="De Jager">Philip L. De Jager</name><affiliation wicri:level="2"><nlm:aff id="A46">Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Department of Neurology & Psychiatry, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Department of Neurology & Psychiatry, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A47">Program in Medical and Population Genetics, Broad Institute, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Deramecourt, Vincent" sort="Deramecourt, Vincent" uniqKey="Deramecourt V" first="Vincent" last="Deramecourt">Vincent Deramecourt</name><affiliation wicri:level="4"><nlm:aff id="A2">Université Lille 2, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Université Lille 2, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement><settlement type="city">Lille</settlement></placeName><orgName type="university">Université Lille 2</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A28">Centre National de Reference pour les Malades Alzheimer Jeunes (CNR-MAJ), Centre Hospitalier Régional Universitaire de Lille, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre National de Reference pour les Malades Alzheimer Jeunes (CNR-MAJ), Centre Hospitalier Régional Universitaire de Lille, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Johnston, Janet A" sort="Johnston, Janet A" uniqKey="Johnston J" first="Janet A" last="Johnston">Janet A. Johnston</name><affiliation wicri:level="1"><nlm:aff id="A43">Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast</wicri:regionArea><wicri:noRegion>Belfast</wicri:noRegion></affiliation></author><author><name sortKey="Evans, Denis" sort="Evans, Denis" uniqKey="Evans D" first="Denis" last="Evans">Denis Evans</name><affiliation wicri:level="2"><nlm:aff id="A48">Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Lovestone, Simon" sort="Lovestone, Simon" uniqKey="Lovestone S" first="Simon" last="Lovestone">Simon Lovestone</name><affiliation wicri:level="3"><nlm:aff id="A49">Institute of Psychiatry, King’s College London, Denmark Hill, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychiatry, King’s College London, Denmark Hill, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Letenneur, Luc" sort="Letenneur, Luc" uniqKey="Letenneur L" first="Luc" last="Letenneur">Luc Letenneur</name><affiliation wicri:level="3"><nlm:aff id="A50">INSERM, U897, Victor Segalen University, Bordeaux, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U897, Victor Segalen University, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Mor N, Francisco J" sort="Mor N, Francisco J" uniqKey="Mor N F" first="Francisco J" last="Mor N">Francisco J. Mor N</name><affiliation wicri:level="1"><nlm:aff id="A51">Departamento de Genómica Estructural, Neocodex, Seville, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Departamento de Genómica Estructural, Neocodex, Seville</wicri:regionArea><wicri:noRegion>Seville</wicri:noRegion></affiliation></author><author><name sortKey="Rubinsztein, David C" sort="Rubinsztein, David C" uniqKey="Rubinsztein D" first="David C" last="Rubinsztein">David C. Rubinsztein</name><affiliation wicri:level="4"><nlm:aff id="A52">Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Cambridge Institute for Medical Research, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Eiriksdottir, Gudny" sort="Eiriksdottir, Gudny" uniqKey="Eiriksdottir G" first="Gudny" last="Eiriksdottir">Gudny Eiriksdottir</name><affiliation wicri:level="1"><nlm:aff id="A18">Icelandic Heart Association, Kopavogur, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation></author><author><name sortKey="Sleegers, Kristel" sort="Sleegers, Kristel" uniqKey="Sleegers K" first="Kristel" last="Sleegers">Kristel Sleegers</name><affiliation wicri:level="1"><nlm:aff id="A53">Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp, Belgium.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Belgique</country><wicri:regionArea>Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp</wicri:regionArea><wicri:noRegion>Antwerp</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A54">Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Belgique</country><wicri:regionArea>Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp</wicri:regionArea><orgName type="university">Université d'Anvers</orgName><placeName><settlement type="city">Anvers</settlement><region>Région flamande</region><region type="district" nuts="2">Province d'Anvers</region></placeName></affiliation></author><author><name sortKey="Goate, Alison M" sort="Goate, Alison M" uniqKey="Goate A" first="Alison M" last="Goate">Alison M. Goate</name><affiliation wicri:level="4"><nlm:aff id="A41">Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A42">Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, Missouri, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation></author><author><name sortKey="Fievet, Nathalie" sort="Fievet, Nathalie" uniqKey="Fievet N" first="Nathalie" last="Fiévet">Nathalie Fiévet</name><affiliation wicri:level="3"><nlm:aff id="A1">INSERM, U744, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U744, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A3">Institut Pasteur de Lille, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur de Lille, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Huentelman, Matthew J" sort="Huentelman, Matthew J" uniqKey="Huentelman M" first="Matthew J" last="Huentelman">Matthew J. Huentelman</name><affiliation wicri:level="2"><nlm:aff id="A55">Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Arizona, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Arizona</wicri:regionArea><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Gill, Michael" sort="Gill, Michael" uniqKey="Gill M" first="Michael" last="Gill">Michael Gill</name><affiliation wicri:level="1"><nlm:aff id="A56">Mercer’s Institute for Research on Aging, St. James Hospital and Trinity College, Dublin, Ireland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Irlande (pays)</country><wicri:regionArea>Mercer’s Institute for Research on Aging, St. James Hospital and Trinity College, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Brown, Kristelle" sort="Brown, Kristelle" uniqKey="Brown K" first="Kristelle" last="Brown">Kristelle Brown</name><affiliation wicri:level="4"><nlm:aff id="A57">Institute of Genetics, Queen’s Medical Centre, University of Nottingham, Nottingham, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Genetics, Queen’s Medical Centre, University of Nottingham, Nottingham</wicri:regionArea><orgName type="university">Université de Nottingham</orgName><placeName><settlement type="city">Nottingham</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Nottinghamshire</region></placeName></affiliation></author><author><name sortKey="Kamboh, M Ilyas" sort="Kamboh, M Ilyas" uniqKey="Kamboh M" first="M Ilyas" last="Kamboh">M Ilyas Kamboh</name><affiliation wicri:level="4"><nlm:aff id="A58">Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region><settlement type="city">Pittsburgh</settlement></placeName><orgName type="university">Université de Pittsburgh</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A59">Alzheimer’s Disease Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Alzheimer’s Disease Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region><settlement type="city">Pittsburgh</settlement></placeName><orgName type="university">Université de Pittsburgh</orgName></affiliation></author><author><name sortKey="Keller, Lina" sort="Keller, Lina" uniqKey="Keller L" first="Lina" last="Keller">Lina Keller</name><affiliation wicri:level="3"><nlm:aff id="A60">Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Barberger Gateau, Pascale" sort="Barberger Gateau, Pascale" uniqKey="Barberger Gateau P" first="Pascale" last="Barberger-Gateau">Pascale Barberger-Gateau</name><affiliation wicri:level="3"><nlm:aff id="A50">INSERM, U897, Victor Segalen University, Bordeaux, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U897, Victor Segalen University, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Mcguinness, Bernadette" sort="Mcguinness, Bernadette" uniqKey="Mcguinness B" first="Bernadette" last="Mcguinness">Bernadette Mcguinness</name><affiliation wicri:level="1"><nlm:aff id="A43">Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast</wicri:regionArea><wicri:noRegion>Belfast</wicri:noRegion></affiliation></author><author><name sortKey="Larson, Eric B" sort="Larson, Eric B" uniqKey="Larson E" first="Eric B" last="Larson">Eric B. Larson</name><affiliation wicri:level="4"><nlm:aff id="A38">Department of Medicine, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="2"><nlm:aff id="A61">Group Health Research Institute, Group Health, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Group Health Research Institute, Group Health, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Green, Robert" sort="Green, Robert" uniqKey="Green R" first="Robert" last="Green">Robert Green</name><affiliation wicri:level="2"><nlm:aff id="A62">Department of Medicine and Partners Center for Personalized Genetic Medicine, Division of Genetics, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine and Partners Center for Personalized Genetic Medicine, Division of Genetics, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Myers, Amanda J" sort="Myers, Amanda J" uniqKey="Myers A" first="Amanda J" last="Myers">Amanda J. Myers</name><affiliation wicri:level="2"><nlm:aff id="A63">Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Dufouil, Carole" sort="Dufouil, Carole" uniqKey="Dufouil C" first="Carole" last="Dufouil">Carole Dufouil</name><affiliation wicri:level="3"><nlm:aff id="A50">INSERM, U897, Victor Segalen University, Bordeaux, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U897, Victor Segalen University, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Todd, Stephen" sort="Todd, Stephen" uniqKey="Todd S" first="Stephen" last="Todd">Stephen Todd</name><affiliation wicri:level="1"><nlm:aff id="A43">Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast</wicri:regionArea><wicri:noRegion>Belfast</wicri:noRegion></affiliation></author><author><name sortKey="Wallon, David" sort="Wallon, David" uniqKey="Wallon D" first="David" last="Wallon">David Wallon</name><affiliation wicri:level="3"><nlm:aff id="A37">CNR-MAJ, INSERM, U1079, Rouen University Hospital, Rouen, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNR-MAJ, INSERM, U1079, Rouen University Hospital, Rouen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Haute-Normandie</region><settlement type="city">Rouen</settlement></placeName></affiliation></author><author><name sortKey="Love, Seth" sort="Love, Seth" uniqKey="Love S" first="Seth" last="Love">Seth Love</name><affiliation wicri:level="1"><nlm:aff id="A64">University of Bristol Institute of Clinical Neurosciences, School of Clinical Sciences, Frenchay Hospital, Bristol, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>University of Bristol Institute of Clinical Neurosciences, School of Clinical Sciences, Frenchay Hospital, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Rogaeva, Ekaterina" sort="Rogaeva, Ekaterina" uniqKey="Rogaeva E" first="Ekaterina" last="Rogaeva">Ekaterina Rogaeva</name><affiliation wicri:level="4"><nlm:aff id="A65">Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Canada</country><wicri:regionArea>Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Gallacher, John" sort="Gallacher, John" uniqKey="Gallacher J" first="John" last="Gallacher">John Gallacher</name><affiliation wicri:level="1"><nlm:aff id="A66">Institute of Primary Care and Public Health, Cardiff University, Neuadd Meirionnydd, University Hospital of Wales, Heath Park, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Primary Care and Public Health, Cardiff University, Neuadd Meirionnydd, University Hospital of Wales, Heath Park, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="St George Hyslop, Peter" sort="St George Hyslop, Peter" uniqKey="St George Hyslop P" first="Peter" last="St George-Hyslop">Peter St George-Hyslop</name><affiliation wicri:level="4"><nlm:aff id="A52">Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Cambridge Institute for Medical Research, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A65">Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Canada</country><wicri:regionArea>Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A67">Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Department of Clinical Neurosciences, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Clarimon, Jordi" sort="Clarimon, Jordi" uniqKey="Clarimon J" first="Jordi" last="Clarimon">Jordi Clarimon</name><affiliation wicri:level="4"><nlm:aff id="A68">Neurology Department. Biomedical Research Institute Sant Pau (IIB Sant Pau). Sant Pau Hospital. Universitat Autònoma de Barcelona, Barcelona, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Neurology Department. Biomedical Research Institute Sant Pau (IIB Sant Pau). Sant Pau Hospital. Universitat Autònoma de Barcelona, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region><settlement type="city">Barcelone</settlement></placeName><orgName type="university">Université autonome de Barcelone</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A69">Center for Networker Biomedical Research in Neurodegenerative Diseases (CIBERNED), Barcelona, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Center for Networker Biomedical Research in Neurodegenerative Diseases (CIBERNED), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Lleo, Alberto" sort="Lleo, Alberto" uniqKey="Lleo A" first="Alberto" last="Lleo">Alberto Lleo</name><affiliation wicri:level="4"><nlm:aff id="A68">Neurology Department. Biomedical Research Institute Sant Pau (IIB Sant Pau). Sant Pau Hospital. Universitat Autònoma de Barcelona, Barcelona, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Neurology Department. Biomedical Research Institute Sant Pau (IIB Sant Pau). Sant Pau Hospital. Universitat Autònoma de Barcelona, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region><settlement type="city">Barcelone</settlement></placeName><orgName type="university">Université autonome de Barcelone</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A69">Center for Networker Biomedical Research in Neurodegenerative Diseases (CIBERNED), Barcelona, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Center for Networker Biomedical Research in Neurodegenerative Diseases (CIBERNED), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Bayer, Anthony" sort="Bayer, Anthony" uniqKey="Bayer A" first="Anthony" last="Bayer">Anthony Bayer</name><affiliation wicri:level="1"><nlm:aff id="A66">Institute of Primary Care and Public Health, Cardiff University, Neuadd Meirionnydd, University Hospital of Wales, Heath Park, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Primary Care and Public Health, Cardiff University, Neuadd Meirionnydd, University Hospital of Wales, Heath Park, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Tsuang, Debby W" sort="Tsuang, Debby W" uniqKey="Tsuang D" first="Debby W" last="Tsuang">Debby W. Tsuang</name><affiliation wicri:level="2"><nlm:aff id="A70">Geriatric Research, Education and Clinical Center (GRECC), Veteran Administration Puget Sound Health Care System (VAPSHCS), Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Geriatric Research, Education and Clinical Center (GRECC), Veteran Administration Puget Sound Health Care System (VAPSHCS), Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Yu, Lei" sort="Yu, Lei" uniqKey="Yu L" first="Lei" last="Yu">Lei Yu</name><affiliation wicri:level="2"><nlm:aff id="A71">Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Tsolaki, Magda" sort="Tsolaki, Magda" uniqKey="Tsolaki M" first="Magda" last="Tsolaki">Magda Tsolaki</name><affiliation wicri:level="1"><nlm:aff id="A72">Department of Neurology, Aristotle University of Thessaloniki, Thessaloniki, Greece.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Grèce</country><wicri:regionArea>Department of Neurology, Aristotle University of Thessaloniki, Thessaloniki</wicri:regionArea><wicri:noRegion>Thessaloniki</wicri:noRegion></affiliation></author><author><name sortKey="Bossu, Paola" sort="Bossu, Paola" uniqKey="Bossu P" first="Paola" last="Bossù">Paola Bossù</name><affiliation wicri:level="3"><nlm:aff id="A73">Clinical and Behavioral Neurology, Fondazione Santa Lucia, Rome, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Clinical and Behavioral Neurology, Fondazione Santa Lucia, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Spalletta, Gianfranco" sort="Spalletta, Gianfranco" uniqKey="Spalletta G" first="Gianfranco" last="Spalletta">Gianfranco Spalletta</name><affiliation wicri:level="3"><nlm:aff id="A73">Clinical and Behavioral Neurology, Fondazione Santa Lucia, Rome, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Clinical and Behavioral Neurology, Fondazione Santa Lucia, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Proitsi, Petroula" sort="Proitsi, Petroula" uniqKey="Proitsi P" first="Petroula" last="Proitsi">Petroula Proitsi</name><affiliation wicri:level="3"><nlm:aff id="A49">Institute of Psychiatry, King’s College London, Denmark Hill, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychiatry, King’s College London, Denmark Hill, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Collinge, John" sort="Collinge, John" uniqKey="Collinge J" first="John" last="Collinge">John Collinge</name><affiliation wicri:level="3"><nlm:aff id="A74">MRC Prion Unit, Department of Neurodegenerative Disease, University College London Institute of Neurology, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Prion Unit, Department of Neurodegenerative Disease, University College London Institute of Neurology, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Sorbi, Sandro" sort="Sorbi, Sandro" uniqKey="Sorbi S" first="Sandro" last="Sorbi">Sandro Sorbi</name><affiliation wicri:level="1"><nlm:aff id="A75">NEUROFARBA (Department of Neuroscience, Psychology, Drug Research and Child Health), University of Florence, Florence, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>NEUROFARBA (Department of Neuroscience, Psychology, Drug Research and Child Health), University of Florence, Florence</wicri:regionArea><wicri:noRegion>Florence</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A76">Centro di Ricerca, Trasferimento e Alta Formazione DENOTHE, University of Florence, Florence, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Centro di Ricerca, Trasferimento e Alta Formazione DENOTHE, University of Florence, Florence</wicri:regionArea><wicri:noRegion>Florence</wicri:noRegion></affiliation></author><author><name sortKey="Sanchez Garcia, Florentino" sort="Sanchez Garcia, Florentino" uniqKey="Sanchez Garcia F" first="Florentino" last="Sanchez-Garcia">Florentino Sanchez-Garcia</name><affiliation wicri:level="1"><nlm:aff id="A77">Department of Immunology, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Immunology, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria</wicri:regionArea><wicri:noRegion>Las Palmas de Gran Canaria</wicri:noRegion></affiliation></author><author><name sortKey="Fox, Nick C" sort="Fox, Nick C" uniqKey="Fox N" first="Nick C" last="Fox">Nick C. Fox</name><affiliation wicri:level="3"><nlm:aff id="A78">Dementia Research Centre, Department of Neurodegenerative Disease, University College London Institute of Neurology, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Dementia Research Centre, Department of Neurodegenerative Disease, University College London Institute of Neurology, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Hardy, John" sort="Hardy, John" uniqKey="Hardy J" first="John" last="Hardy">John Hardy</name><affiliation wicri:level="3"><nlm:aff id="A79">Department of Molecular Neuroscience, Institute of Neurology, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Department of Molecular Neuroscience, Institute of Neurology, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A80">Reta Lilla Weston Laboratories, Institute of Neurology, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Reta Lilla Weston Laboratories, Institute of Neurology, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Deniz Naranjo, Maria Candida" sort="Deniz Naranjo, Maria Candida" uniqKey="Deniz Naranjo M" first="Maria Candida" last="Deniz Naranjo">Maria Candida Deniz Naranjo</name><affiliation wicri:level="1"><nlm:aff id="A77">Department of Immunology, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Immunology, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria</wicri:regionArea><wicri:noRegion>Las Palmas de Gran Canaria</wicri:noRegion></affiliation></author><author><name sortKey="Bosco, Paolo" sort="Bosco, Paolo" uniqKey="Bosco P" first="Paolo" last="Bosco">Paolo Bosco</name><affiliation wicri:level="1"><nlm:aff id="A81">Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Associazione Oasi Maria Santissima Srl, Troina, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Associazione Oasi Maria Santissima Srl, Troina</wicri:regionArea><wicri:noRegion>Troina</wicri:noRegion></affiliation></author><author><name sortKey="Clarke, Robert" sort="Clarke, Robert" uniqKey="Clarke R" first="Robert" last="Clarke">Robert Clarke</name><affiliation wicri:level="4"><nlm:aff id="A82">Oxford Healthy Aging Project (OHAP), Clinical Trial Service Unit, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Oxford Healthy Aging Project (OHAP), Clinical Trial Service Unit, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Brayne, Carol" sort="Brayne, Carol" uniqKey="Brayne C" first="Carol" last="Brayne">Carol Brayne</name><affiliation wicri:level="4"><nlm:aff id="A83">Institute of Public Health, University of Cambridge, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Public Health, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Galimberti, Daniela" sort="Galimberti, Daniela" uniqKey="Galimberti D" first="Daniela" last="Galimberti">Daniela Galimberti</name><affiliation wicri:level="3"><nlm:aff id="A84">University of Milan, Fondazione Cà Granda, IRCCS Ospedale Policlinico, Milan, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>University of Milan, Fondazione Cà Granda, IRCCS Ospedale Policlinico, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Mancuso, Michelangelo" sort="Mancuso, Michelangelo" uniqKey="Mancuso M" first="Michelangelo" last="Mancuso">Michelangelo Mancuso</name><affiliation wicri:level="4"><nlm:aff id="A85">Neurological Clinic, University of Pisa, Pisa, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Neurological Clinic, University of Pisa, Pisa</wicri:regionArea><placeName><settlement type="city">Pise</settlement><region nuts="2">Toscane</region><settlement type="city">Pise</settlement></placeName><orgName type="university">Université de Pise</orgName></affiliation></author><author><name sortKey="Matthews, Fiona" sort="Matthews, Fiona" uniqKey="Matthews F" first="Fiona" last="Matthews">Fiona Matthews</name><affiliation wicri:level="1"><nlm:aff id="A86">MRC Biostatistics Unit, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Biostatistics Unit, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Moebus, Susanne" sort="Moebus, Susanne" uniqKey="Moebus S" first="Susanne" last="Moebus">Susanne Moebus</name><affiliation wicri:level="1"><nlm:aff id="A88">Urban Epidemiology, Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Urban Epidemiology, Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University Duisburg-Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Mecocci, Patrizia" sort="Mecocci, Patrizia" uniqKey="Mecocci P" first="Patrizia" last="Mecocci">Patrizia Mecocci</name><affiliation wicri:level="1"><nlm:aff id="A89">Section of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Section of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia</wicri:regionArea><wicri:noRegion>Perugia</wicri:noRegion></affiliation></author><author><name sortKey="Zompo, Maria Del" sort="Zompo, Maria Del" uniqKey="Zompo M" first="Maria Del" last="Zompo">Maria Del Zompo</name><affiliation wicri:level="1"><nlm:aff id="A90">Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, Cagliari</wicri:regionArea><wicri:noRegion>Cagliari</wicri:noRegion></affiliation></author><author><name sortKey="Maier, Wolfgang" sort="Maier, Wolfgang" uniqKey="Maier W" first="Wolfgang" last="Maier">Wolfgang Maier</name><affiliation wicri:level="3"><nlm:aff id="A29">Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Psychiatry and Psychotherapy, University of Bonn, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A39">German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>German Center for Neurodegenerative Diseases (DZNE), Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation></author><author><name sortKey="Hampel, Harald" sort="Hampel, Harald" uniqKey="Hampel H" first="Harald" last="Hampel">Harald Hampel</name><affiliation wicri:level="3"><nlm:aff id="A91">Department of Psychiatry, University of Frankfurt, Frankfurt am Main, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Psychiatry, University of Frankfurt, Frankfurt am Main</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A92">Department of Psychiatry, Ludwig Maximilians University, Munich, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Psychiatry, Ludwig Maximilians University, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Pilotto, Alberto" sort="Pilotto, Alberto" uniqKey="Pilotto A" first="Alberto" last="Pilotto">Alberto Pilotto</name><affiliation wicri:level="1"><nlm:aff id="A93">Gerontology and Geriatrics Research Laboratory, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Gerontology and Geriatrics Research Laboratory, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo</wicri:regionArea><wicri:noRegion>San Giovanni Rotondo</wicri:noRegion></affiliation></author><author><name sortKey="Bullido, Maria" sort="Bullido, Maria" uniqKey="Bullido M" first="Maria" last="Bullido">Maria Bullido</name><affiliation wicri:level="4"><nlm:aff id="A94">Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas–Universidad Autónoma de Madrid, Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas–Universidad Autónoma de Madrid, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region><settlement type="city">Madrid</settlement></placeName><orgName type="university">Université autonome de Madrid</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A95">Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A96">Instituto de Investigación Sanitaria Hospital la Paz (IdIPaz), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Instituto de Investigación Sanitaria Hospital la Paz (IdIPaz), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Panza, Francesco" sort="Panza, Francesco" uniqKey="Panza F" first="Francesco" last="Panza">Francesco Panza</name><affiliation wicri:level="1"><nlm:aff id="A97">Departement of Geriatrics, Center for Aging Brain, University of Bari, Bari, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Departement of Geriatrics, Center for Aging Brain, University of Bari, Bari</wicri:regionArea><wicri:noRegion>Bari</wicri:noRegion></affiliation></author><author><name sortKey="Caffarra, Paolo" sort="Caffarra, Paolo" uniqKey="Caffarra P" first="Paolo" last="Caffarra">Paolo Caffarra</name><affiliation wicri:level="1"><nlm:aff id="A98">Department of Neuroscience, University of Parma, Parma, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Department of Neuroscience, University of Parma, Parma</wicri:regionArea><wicri:noRegion>Parma</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A99">Center for Cognitive Disorders, Azienda Unita Sanitaria Local (AUSL), Parma, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Center for Cognitive Disorders, Azienda Unita Sanitaria Local (AUSL), Parma</wicri:regionArea><wicri:noRegion>Parma</wicri:noRegion></affiliation></author><author><name sortKey="Nacmias, Benedetta" sort="Nacmias, Benedetta" uniqKey="Nacmias B" first="Benedetta" last="Nacmias">Benedetta Nacmias</name><affiliation wicri:level="1"><nlm:aff id="A75">NEUROFARBA (Department of Neuroscience, Psychology, Drug Research and Child Health), University of Florence, Florence, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>NEUROFARBA (Department of Neuroscience, Psychology, Drug Research and Child Health), University of Florence, Florence</wicri:regionArea><wicri:noRegion>Florence</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A76">Centro di Ricerca, Trasferimento e Alta Formazione DENOTHE, University of Florence, Florence, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Centro di Ricerca, Trasferimento e Alta Formazione DENOTHE, University of Florence, Florence</wicri:regionArea><wicri:noRegion>Florence</wicri:noRegion></affiliation></author><author><name sortKey="Gilbert, John R" sort="Gilbert, John R" uniqKey="Gilbert J" first="John R" last="Gilbert">John R. Gilbert</name><affiliation wicri:level="2"><nlm:aff id="A13">John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A14">Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Mayhaus, Manuel" sort="Mayhaus, Manuel" uniqKey="Mayhaus M" first="Manuel" last="Mayhaus">Manuel Mayhaus</name><affiliation wicri:level="1"><nlm:aff id="A100">Department of Psychiatry, Saarland University Hospital, Homburg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Psychiatry, Saarland University Hospital, Homburg</wicri:regionArea><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion></affiliation></author><author><name sortKey="Lannfelt, Lars" sort="Lannfelt, Lars" uniqKey="Lannfelt L" first="Lars" last="Lannfelt">Lars Lannfelt</name><affiliation wicri:level="4"><nlm:aff id="A101">Department of Public Health/Geriatrics, Uppsala University, Uppsala, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Department of Public Health/Geriatrics, Uppsala University, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Hakonarson, Hakon" sort="Hakonarson, Hakon" uniqKey="Hakonarson H" first="Hakon" last="Hakonarson">Hakon Hakonarson</name><affiliation wicri:level="2"><nlm:aff id="A102">Center for Applied Genomics, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Center for Applied Genomics, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Pichler, Sabrina" sort="Pichler, Sabrina" uniqKey="Pichler S" first="Sabrina" last="Pichler">Sabrina Pichler</name><affiliation wicri:level="1"><nlm:aff id="A100">Department of Psychiatry, Saarland University Hospital, Homburg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Psychiatry, Saarland University Hospital, Homburg</wicri:regionArea><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion></affiliation></author><author><name sortKey="Carrasquillo, Minerva M" sort="Carrasquillo, Minerva M" uniqKey="Carrasquillo M" first="Minerva M" last="Carrasquillo">Minerva M. Carrasquillo</name><affiliation wicri:level="2"><nlm:aff id="A103">Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Neuroscience, Mayo Clinic, Jacksonville, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Ingelsson, Martin" sort="Ingelsson, Martin" uniqKey="Ingelsson M" first="Martin" last="Ingelsson">Martin Ingelsson</name><affiliation wicri:level="4"><nlm:aff id="A101">Department of Public Health/Geriatrics, Uppsala University, Uppsala, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Department of Public Health/Geriatrics, Uppsala University, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Beekly, Duane" sort="Beekly, Duane" uniqKey="Beekly D" first="Duane" last="Beekly">Duane Beekly</name><affiliation wicri:level="4"><nlm:aff id="A104">National Alzheimer’s Coordinating Center, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>National Alzheimer’s Coordinating Center, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Alvarez, Victoria" sort="Alvarez, Victoria" uniqKey="Alvarez V" first="Victoria" last="Alvarez">Victoria Alvarez</name><affiliation wicri:level="1"><nlm:aff id="A105">Genetica Molecular, Hospital Universitario Central Asturias, Oviedo, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Genetica Molecular, Hospital Universitario Central Asturias, Oviedo</wicri:regionArea><wicri:noRegion>Oviedo</wicri:noRegion></affiliation></author><author><name sortKey="Zou, Fanggeng" sort="Zou, Fanggeng" uniqKey="Zou F" first="Fanggeng" last="Zou">Fanggeng Zou</name><affiliation wicri:level="2"><nlm:aff id="A103">Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Neuroscience, Mayo Clinic, Jacksonville, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Valladares, Otto" sort="Valladares, Otto" uniqKey="Valladares O" first="Otto" last="Valladares">Otto Valladares</name><affiliation wicri:level="2"><nlm:aff id="A23">Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Younkin, Steven G" sort="Younkin, Steven G" uniqKey="Younkin S" first="Steven G" last="Younkin">Steven G. Younkin</name><affiliation wicri:level="2"><nlm:aff id="A103">Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Neuroscience, Mayo Clinic, Jacksonville, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Coto, Eliecer" sort="Coto, Eliecer" uniqKey="Coto E" first="Eliecer" last="Coto">Eliecer Coto</name><affiliation wicri:level="1"><nlm:aff id="A105">Genetica Molecular, Hospital Universitario Central Asturias, Oviedo, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Genetica Molecular, Hospital Universitario Central Asturias, Oviedo</wicri:regionArea><wicri:noRegion>Oviedo</wicri:noRegion></affiliation></author><author><name sortKey="Hamilton Nelson, Kara L" sort="Hamilton Nelson, Kara L" uniqKey="Hamilton Nelson K" first="Kara L" last="Hamilton-Nelson">Kara L. Hamilton-Nelson</name><affiliation wicri:level="2"><nlm:aff id="A13">John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Gu, Wei" sort="Gu, Wei" uniqKey="Gu W" first="Wei" last="Gu">Wei Gu</name><affiliation wicri:level="1"><nlm:aff id="A100">Department of Psychiatry, Saarland University Hospital, Homburg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Psychiatry, Saarland University Hospital, Homburg</wicri:regionArea><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion></affiliation></author><author><name sortKey="Razquin, Cristina" sort="Razquin, Cristina" uniqKey="Razquin C" first="Cristina" last="Razquin">Cristina Razquin</name><affiliation wicri:level="1"><nlm:aff id="A106">Neurogenetics Laboratory, Division of Neurosciences, Center for Applied Medical Research, University of Navarra School of Medicine, Pamplona, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Neurogenetics Laboratory, Division of Neurosciences, Center for Applied Medical Research, University of Navarra School of Medicine, Pamplona</wicri:regionArea><wicri:noRegion>Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="Pastor, Pau" sort="Pastor, Pau" uniqKey="Pastor P" first="Pau" last="Pastor">Pau Pastor</name><affiliation wicri:level="1"><nlm:aff id="A106">Neurogenetics Laboratory, Division of Neurosciences, Center for Applied Medical Research, University of Navarra School of Medicine, Pamplona, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Neurogenetics Laboratory, Division of Neurosciences, Center for Applied Medical Research, University of Navarra School of Medicine, Pamplona</wicri:regionArea><wicri:noRegion>Pamplona</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A107">CIBERNED, Instituto de Salud Carlos III, Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>CIBERNED, Instituto de Salud Carlos III, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Mateo, Ignacio" sort="Mateo, Ignacio" uniqKey="Mateo I" first="Ignacio" last="Mateo">Ignacio Mateo</name><affiliation wicri:level="1"><nlm:aff id="A108">Neurology Service, Marqués de Valdecilla University Hospital, University of Cantabria and Instituto de Formación e Investigación Marqués de Valdecilla (IFIMAV), Santander, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Neurology Service, Marqués de Valdecilla University Hospital, University of Cantabria and Instituto de Formación e Investigación Marqués de Valdecilla (IFIMAV), Santander</wicri:regionArea><wicri:noRegion>Santander</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A109">CIBERNED, Marqués de Valdecilla University Hospital, University of Cantabria and IFIMAV, Santander, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>CIBERNED, Marqués de Valdecilla University Hospital, University of Cantabria and IFIMAV, Santander</wicri:regionArea><wicri:noRegion>Santander</wicri:noRegion></affiliation></author><author><name sortKey="Owen, Michael J" sort="Owen, Michael J" uniqKey="Owen M" first="Michael J" last="Owen">Michael J. Owen</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Faber, Kelley M" sort="Faber, Kelley M" uniqKey="Faber K" first="Kelley M" last="Faber">Kelley M. Faber</name><affiliation wicri:level="2"><nlm:aff id="A110">Department of Medical and Molecular Genetics, Indiana University, Indianapolis, Indiana, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medical and Molecular Genetics, Indiana University, Indianapolis, Indiana</wicri:regionArea><placeName><region type="state">Indiana</region></placeName></affiliation></author><author><name sortKey="Jonsson, Palmi V" sort="Jonsson, Palmi V" uniqKey="Jonsson P" first="Palmi V" last="Jonsson">Palmi V. Jonsson</name><affiliation wicri:level="1"><nlm:aff id="A17">Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A111">Geriatric Department, Landspitali University Hospital, Reykjavik, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Geriatric Department, Landspitali University Hospital, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Combarros, Onofre" sort="Combarros, Onofre" uniqKey="Combarros O" first="Onofre" last="Combarros">Onofre Combarros</name><affiliation wicri:level="1"><nlm:aff id="A108">Neurology Service, Marqués de Valdecilla University Hospital, University of Cantabria and Instituto de Formación e Investigación Marqués de Valdecilla (IFIMAV), Santander, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Neurology Service, Marqués de Valdecilla University Hospital, University of Cantabria and Instituto de Formación e Investigación Marqués de Valdecilla (IFIMAV), Santander</wicri:regionArea><wicri:noRegion>Santander</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A109">CIBERNED, Marqués de Valdecilla University Hospital, University of Cantabria and IFIMAV, Santander, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>CIBERNED, Marqués de Valdecilla University Hospital, University of Cantabria and IFIMAV, Santander</wicri:regionArea><wicri:noRegion>Santander</wicri:noRegion></affiliation></author><author><name sortKey="O Onovan, Michael C" sort="O Onovan, Michael C" uniqKey="O Onovan M" first="Michael C" last="O Onovan">Michael C. O Onovan</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Cantwell, Laura B" sort="Cantwell, Laura B" uniqKey="Cantwell L" first="Laura B" last="Cantwell">Laura B. Cantwell</name><affiliation wicri:level="2"><nlm:aff id="A23">Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Soininen, Hilkka" sort="Soininen, Hilkka" uniqKey="Soininen H" first="Hilkka" last="Soininen">Hilkka Soininen</name><affiliation wicri:level="1"><nlm:aff id="A112">Institute of Clinical Medicine–Neurology, University of Eastern Finland, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Institute of Clinical Medicine–Neurology, University of Eastern Finland, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A113">Department of Neurology, Kuopio University Hospital, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Neurology, Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Blacker, Deborah" sort="Blacker, Deborah" uniqKey="Blacker D" first="Deborah" last="Blacker">Deborah Blacker</name><affiliation wicri:level="2"><nlm:aff id="A114">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A115">Department of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Mead, Simon" sort="Mead, Simon" uniqKey="Mead S" first="Simon" last="Mead">Simon Mead</name><affiliation wicri:level="3"><nlm:aff id="A74">MRC Prion Unit, Department of Neurodegenerative Disease, University College London Institute of Neurology, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Prion Unit, Department of Neurodegenerative Disease, University College London Institute of Neurology, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Mosley, Thomas H" sort="Mosley, Thomas H" uniqKey="Mosley T" first="Thomas H" last="Mosley">Thomas H. Mosley</name><affiliation wicri:level="2"><nlm:aff id="A116">Department of Medicine (Geriatrics), University of Mississippi Medical Center, Jackson, Mississippi, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine (Geriatrics), University of Mississippi Medical Center, Jackson, Mississippi</wicri:regionArea><placeName><region type="state">État du Mississippi</region></placeName></affiliation></author><author><name sortKey="Bennett, David A" sort="Bennett, David A" uniqKey="Bennett D" first="David A" last="Bennett">David A. Bennett</name><affiliation wicri:level="2"><nlm:aff id="A71">Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A117">Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B" last="Harris">Tamara B. Harris</name><affiliation wicri:level="4"><nlm:aff id="A12">Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Fratiglioni, Laura" sort="Fratiglioni, Laura" uniqKey="Fratiglioni L" first="Laura" last="Fratiglioni">Laura Fratiglioni</name><affiliation wicri:level="3"><nlm:aff id="A60">Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A118">Department of Geriatric Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Department of Geriatric Medicine, Karolinska University Hospital Huddinge, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Holmes, Clive" sort="Holmes, Clive" uniqKey="Holmes C" first="Clive" last="Holmes">Clive Holmes</name><affiliation wicri:level="1"><nlm:aff id="A119">Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton</wicri:regionArea><wicri:noRegion>Southampton</wicri:noRegion></affiliation></author><author><name sortKey="De Bruijn, Renee F A G" sort="De Bruijn, Renee F A G" uniqKey="De Bruijn R" first="Renee F A G" last="De Bruijn">Renee F A G. De Bruijn</name><affiliation wicri:level="3"><nlm:aff id="A4">Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Neurology, Erasmus MC University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A20">Netherlands Consortium for Healthy Aging, Leiden, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherlands Consortium for Healthy Aging, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Passmore, Peter" sort="Passmore, Peter" uniqKey="Passmore P" first="Peter" last="Passmore">Peter Passmore</name><affiliation wicri:level="1"><nlm:aff id="A43">Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast</wicri:regionArea><wicri:noRegion>Belfast</wicri:noRegion></affiliation></author><author><name sortKey="Montine, Thomas J" sort="Montine, Thomas J" uniqKey="Montine T" first="Thomas J" last="Montine">Thomas J. Montine</name><affiliation wicri:level="4"><nlm:aff id="A120">Department of Pathology, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Pathology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Bettens, Karolien" sort="Bettens, Karolien" uniqKey="Bettens K" first="Karolien" last="Bettens">Karolien Bettens</name><affiliation wicri:level="1"><nlm:aff id="A53">Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp, Belgium.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Belgique</country><wicri:regionArea>Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp</wicri:regionArea><wicri:noRegion>Antwerp</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A54">Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Belgique</country><wicri:regionArea>Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp</wicri:regionArea><orgName type="university">Université d'Anvers</orgName><placeName><settlement type="city">Anvers</settlement><region>Région flamande</region><region type="district" nuts="2">Province d'Anvers</region></placeName></affiliation></author><author><name sortKey="Rotter, Jerome I" sort="Rotter, Jerome I" uniqKey="Rotter J" first="Jerome I" last="Rotter">Jerome I. Rotter</name><affiliation wicri:level="2"><nlm:aff id="A121">Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Brice, Alexis" sort="Brice, Alexis" uniqKey="Brice A" first="Alexis" last="Brice">Alexis Brice</name><affiliation wicri:level="4"><nlm:aff id="A122">INSERM UMRS 975, CNRS UMR 7225, Université Pierre et Marie Curie, Centre de Recherche de l’Institut du Cerveau et de la Moëlle Epinière (CRICM), Hôpital de la Salpêtrière, Paris, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM UMRS 975, CNRS UMR 7225, Université Pierre et Marie Curie, Centre de Recherche de l’Institut du Cerveau et de la Moëlle Epinière (CRICM), Hôpital de la Salpêtrière, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement><settlement type="city">Paris</settlement></placeName><orgName type="university">Université Pierre-et-Marie-Curie</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A123">Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital de la Pitié–Salpêtrière, Paris, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital de la Pitié–Salpêtrière, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Morgan, Kevin" sort="Morgan, Kevin" uniqKey="Morgan K" first="Kevin" last="Morgan">Kevin Morgan</name><affiliation wicri:level="4"><nlm:aff id="A57">Institute of Genetics, Queen’s Medical Centre, University of Nottingham, Nottingham, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Genetics, Queen’s Medical Centre, University of Nottingham, Nottingham</wicri:regionArea><orgName type="university">Université de Nottingham</orgName><placeName><settlement type="city">Nottingham</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Nottinghamshire</region></placeName></affiliation></author><author><name sortKey="Foroud, Tatiana M" sort="Foroud, Tatiana M" uniqKey="Foroud T" first="Tatiana M" last="Foroud">Tatiana M. Foroud</name><affiliation wicri:level="2"><nlm:aff id="A110">Department of Medical and Molecular Genetics, Indiana University, Indianapolis, Indiana, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medical and Molecular Genetics, Indiana University, Indianapolis, Indiana</wicri:regionArea><placeName><region type="state">Indiana</region></placeName></affiliation></author><author><name sortKey="Kukull, Walter A" sort="Kukull, Walter A" uniqKey="Kukull W" first="Walter A" last="Kukull">Walter A. Kukull</name><affiliation wicri:level="4"><nlm:aff id="A32">Department of Epidemiology, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Hannequin, Didier" sort="Hannequin, Didier" uniqKey="Hannequin D" first="Didier" last="Hannequin">Didier Hannequin</name><affiliation wicri:level="3"><nlm:aff id="A37">CNR-MAJ, INSERM, U1079, Rouen University Hospital, Rouen, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNR-MAJ, INSERM, U1079, Rouen University Hospital, Rouen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Haute-Normandie</region><settlement type="city">Rouen</settlement></placeName></affiliation></author><author><name sortKey="Powell, John F" sort="Powell, John F" uniqKey="Powell J" first="John F" last="Powell">John F. Powell</name><affiliation wicri:level="3"><nlm:aff id="A49">Institute of Psychiatry, King’s College London, Denmark Hill, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychiatry, King’s College London, Denmark Hill, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Nalls, Michael A" sort="Nalls, Michael A" uniqKey="Nalls M" first="Michael A" last="Nalls">Michael A. Nalls</name><affiliation wicri:level="2"><nlm:aff id="A124">Laboratory of Neurogenetics, Intramural Research Program, National Institute on Aging, Bethesda, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Laboratory of Neurogenetics, Intramural Research Program, National Institute on Aging, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Ritchie, Karen" sort="Ritchie, Karen" uniqKey="Ritchie K" first="Karen" last="Ritchie">Karen Ritchie</name><affiliation wicri:level="3"><nlm:aff id="A44">INSERM, U1061, Faculty of Medicine, Hôpital La Colombière, Montpellier, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U1061, Faculty of Medicine, Hôpital La Colombière, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A125">Faculty of Medicine, Imperial College, St. Mary’s Hospital, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Faculty of Medicine, Imperial College, St. Mary’s Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Lunetta, Kathryn L" sort="Lunetta, Kathryn L" uniqKey="Lunetta K" first="Kathryn L" last="Lunetta">Kathryn L. Lunetta</name><affiliation wicri:level="2"><nlm:aff id="A11">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Kauwe, John S K" sort="Kauwe, John S K" uniqKey="Kauwe J" first="John S K" last="Kauwe">John S K. Kauwe</name><affiliation wicri:level="2"><nlm:aff id="A126">Department of Biology, Brigham Young University, Provo, Utah, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biology, Brigham Young University, Provo, Utah</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation></author><author><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><affiliation wicri:level="2"><nlm:aff id="A127">Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A128">Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A129">Division of Epidemiology, University of Texas Health Sciences Center at Houston, Houston, Texas, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Division of Epidemiology, University of Texas Health Sciences Center at Houston, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Riemenschneider, Matthias" sort="Riemenschneider, Matthias" uniqKey="Riemenschneider M" first="Matthias" last="Riemenschneider">Matthias Riemenschneider</name><affiliation wicri:level="1"><nlm:aff id="A100">Department of Psychiatry, Saarland University Hospital, Homburg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Psychiatry, Saarland University Hospital, Homburg</wicri:regionArea><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion></affiliation></author><author><name sortKey="Boada, Merce" sort="Boada, Merce" uniqKey="Boada M" first="Mercè" last="Boada">Mercè Boada</name><affiliation wicri:level="3"><nlm:aff id="A25">Memory Clinic of Fundació Alzheimer Centre Educacional (ACE). Institut Català de Neurociències Aplicades, Barcelona, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Memory Clinic of Fundació Alzheimer Centre Educacional (ACE). Institut Català de Neurociències Aplicades, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A130">Hospital Universitari Vall d’Hebron–Institut de Recerca, Universitat Autònoma de Barcelona. (VHIR-UAB), Barcelona, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Hospital Universitari Vall d’Hebron–Institut de Recerca, Universitat Autònoma de Barcelona. (VHIR-UAB), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Hiltunen, Mikko" sort="Hiltunen, Mikko" uniqKey="Hiltunen M" first="Mikko" last="Hiltunen">Mikko Hiltunen</name><affiliation wicri:level="1"><nlm:aff id="A112">Institute of Clinical Medicine–Neurology, University of Eastern Finland, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Institute of Clinical Medicine–Neurology, University of Eastern Finland, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A113">Department of Neurology, Kuopio University Hospital, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Neurology, Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Martin, Eden R" sort="Martin, Eden R" uniqKey="Martin E" first="Eden R" last="Martin">Eden R. Martin</name><affiliation wicri:level="2"><nlm:aff id="A13">John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A14">Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Schmidt, Reinhold" sort="Schmidt, Reinhold" uniqKey="Schmidt R" first="Reinhold" last="Schmidt">Reinhold Schmidt</name><affiliation wicri:level="1"><nlm:aff id="A131">Department of Neurology, Medical University of Graz, Graz, Austria.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Autriche</country><wicri:regionArea>Department of Neurology, Medical University of Graz, Graz</wicri:regionArea><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Rujescu, Dan" sort="Rujescu, Dan" uniqKey="Rujescu D" first="Dan" last="Rujescu">Dan Rujescu</name><affiliation wicri:level="1"><nlm:aff id="A132">Department of Psychiatry, University of Halle, Halle, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Psychiatry, University of Halle, Halle</wicri:regionArea><wicri:noRegion>Halle</wicri:noRegion><wicri:noRegion>Halle</wicri:noRegion><wicri:noRegion>Halle</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Li San" sort="Wang, Li San" uniqKey="Wang L" first="Li-San" last="Wang">Li-San Wang</name><affiliation wicri:level="2"><nlm:aff id="A23">Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Dartigues, Jean Francois" sort="Dartigues, Jean Francois" uniqKey="Dartigues J" first="Jean-François" last="Dartigues">Jean-François Dartigues</name><affiliation wicri:level="3"><nlm:aff id="A50">INSERM, U897, Victor Segalen University, Bordeaux, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U897, Victor Segalen University, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A133">Centre de Mémoire de Ressources et de Recherche de Bordeaux, Centre Hospitalier Universitaire (CHU) de Bordeaux, Bordeaux, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre de Mémoire de Ressources et de Recherche de Bordeaux, Centre Hospitalier Universitaire (CHU) de Bordeaux, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Mayeux, Richard" sort="Mayeux, Richard" uniqKey="Mayeux R" first="Richard" last="Mayeux">Richard Mayeux</name><affiliation wicri:level="4"><nlm:aff id="A26">Taub Institute on Alzheimer’s Disease and the Aging Brain, Department of Neurology, Columbia University, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Taub Institute on Alzheimer’s Disease and the Aging Brain, Department of Neurology, Columbia University, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A27">Gertrude H. Sergievsky Center, Department of Neurology, Columbia University, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Gertrude H. Sergievsky Center, Department of Neurology, Columbia University, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Tzourio, Christophe" sort="Tzourio, Christophe" uniqKey="Tzourio C" first="Christophe" last="Tzourio">Christophe Tzourio</name><affiliation wicri:level="3"><nlm:aff id="A134">INSERM, U708, Victor Segalen University, Bordeaux, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U708, Victor Segalen University, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A20">Netherlands Consortium for Healthy Aging, Leiden, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherlands Consortium for Healthy Aging, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Nothen, Markus M" sort="Nothen, Markus M" uniqKey="Nothen M" first="Markus M" last="Nöthen">Markus M. Nöthen</name><affiliation wicri:level="3"><nlm:aff id="A135">Institute of Human Genetics, Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Department of Genomics, Life and Brain Center, University of Bonn, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation></author><author><name sortKey="Graff, Caroline" sort="Graff, Caroline" uniqKey="Graff C" first="Caroline" last="Graff">Caroline Graff</name><affiliation wicri:level="2"><nlm:aff id="A117">Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A136">Department of Neurobiology, Karolinska Institutet, Care Sciences and Society, Karolinska Institute–Alzheimer’s Disease Research Center (KIADRC), Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Department of Neurobiology, Karolinska Institutet, Care Sciences and Society, Karolinska Institute–Alzheimer’s Disease Research Center (KIADRC), Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M" last="Psaty">Bruce M. Psaty</name><affiliation wicri:level="4"><nlm:aff id="A12">Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A32">Department of Epidemiology, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="2"><nlm:aff id="A61">Group Health Research Institute, Group Health, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Group Health Research Institute, Group Health, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A137">Department of Health Service, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Health Service, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Jones, Lesley" sort="Jones, Lesley" uniqKey="Jones L" first="Lesley" last="Jones">Lesley Jones</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Haines, Jonathan L" sort="Haines, Jonathan L" uniqKey="Haines J" first="Jonathan L" last="Haines">Jonathan L. Haines</name><affiliation wicri:level="2"><nlm:aff id="A16">Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A138">Vanderbilt Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Vanderbilt Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Holmans, Peter A" sort="Holmans, Peter A" uniqKey="Holmans P" first="Peter A" last="Holmans">Peter A. Holmans</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Lathrop, Mark" sort="Lathrop, Mark" uniqKey="Lathrop M" first="Mark" last="Lathrop">Mark Lathrop</name><affiliation wicri:level="3"><nlm:aff id="A21">Centre National de Génotypage, Institut Génomique, Commissariat à l’Energie Atomique, Evry, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre National de Génotypage, Institut Génomique, Commissariat à l’Energie Atomique, Evry</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Évry (Essonne)</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A22">Fondation Jean Dausset, Centre d’Etude du Polymorphisme Humain (CEPH), Paris, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Fondation Jean Dausset, Centre d’Etude du Polymorphisme Humain (CEPH), Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A139">McGill University and Génome Québec Innovation Centre, Montreal, Quebec, Canada.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Canada</country><wicri:regionArea>McGill University and Génome Québec Innovation Centre, Montreal, Quebec</wicri:regionArea><wicri:noRegion>Quebec</wicri:noRegion></affiliation></author><author><name sortKey="Pericak Vance, Margaret A" sort="Pericak Vance, Margaret A" uniqKey="Pericak Vance M" first="Margaret A" last="Pericak-Vance">Margaret A. Pericak-Vance</name><affiliation wicri:level="2"><nlm:aff id="A13">John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A14">Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J" last="Launer">Lenore J. Launer</name><affiliation wicri:level="2"><nlm:aff id="A140">Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, Bethesda, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Farrer, Lindsay A" sort="Farrer, Lindsay A" uniqKey="Farrer L" first="Lindsay A" last="Farrer">Lindsay A. Farrer</name><affiliation wicri:level="2"><nlm:aff id="A9">Department of Medicine (Biomedical Genetics), Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine (Biomedical Genetics), Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A10">Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A11">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A141">Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A142">Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Neurology, Boston University School of Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A20">Netherlands Consortium for Healthy Aging, Leiden, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherlands Consortium for Healthy Aging, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A143">Center for Medical Systems Biology, Leiden, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Center for Medical Systems Biology, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Van Broeckhoven, Christine" sort="Van Broeckhoven, Christine" uniqKey="Van Broeckhoven C" first="Christine" last="Van Broeckhoven">Christine Van Broeckhoven</name><affiliation wicri:level="1"><nlm:aff id="A53">Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp, Belgium.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Belgique</country><wicri:regionArea>Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp</wicri:regionArea><wicri:noRegion>Antwerp</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A54">Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Belgique</country><wicri:regionArea>Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp</wicri:regionArea><orgName type="university">Université d'Anvers</orgName><placeName><settlement type="city">Anvers</settlement><region>Région flamande</region><region type="district" nuts="2">Province d'Anvers</region></placeName></affiliation></author><author><name sortKey="Moskvina, Valentina" sort="Moskvina, Valentina" uniqKey="Moskvina V" first="Valentina" last="Moskvina">Valentina Moskvina</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Seshadri, Sudha" sort="Seshadri, Sudha" uniqKey="Seshadri S" first="Sudha" last="Seshadri">Sudha Seshadri</name><affiliation wicri:level="2"><nlm:aff id="A142">Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Neurology, Boston University School of Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Williams, Julie" sort="Williams, Julie" uniqKey="Williams J" first="Julie" last="Williams">Julie Williams</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Schellenberg, Gerard D" sort="Schellenberg, Gerard D" uniqKey="Schellenberg G" first="Gerard D" last="Schellenberg">Gerard D. Schellenberg</name><affiliation wicri:level="2"><nlm:aff id="A23">Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Amouyel, Philippe" sort="Amouyel, Philippe" uniqKey="Amouyel P" first="Philippe" last="Amouyel">Philippe Amouyel</name><affiliation wicri:level="3"><nlm:aff id="A1">INSERM, U744, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U744, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A2">Université Lille 2, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Université Lille 2, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement><settlement type="city">Lille</settlement></placeName><orgName type="university">Université Lille 2</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A3">Institut Pasteur de Lille, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur de Lille, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A28">Centre National de Reference pour les Malades Alzheimer Jeunes (CNR-MAJ), Centre Hospitalier Régional Universitaire de Lille, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre National de Reference pour les Malades Alzheimer Jeunes (CNR-MAJ), Centre Hospitalier Régional Universitaire de Lille, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A144">Centre Hospitalier Régional Universitaire de Lille, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre Hospitalier Régional Universitaire de Lille, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24162737</idno><idno type="pmc">3896259</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896259</idno><idno type="RBID">PMC:3896259</idno><idno type="doi">10.1038/ng.2802</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">000867</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000867</idno><idno type="wicri:Area/Pmc/Curation">000867</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000867</idno><idno type="wicri:Area/Pmc/Checkpoint">000629</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000629</idno><idno type="wicri:Area/Ncbi/Merge">001600</idno><idno type="wicri:Area/Ncbi/Curation">001600</idno><idno type="wicri:Area/Ncbi/Checkpoint">001600</idno><idno type="wicri:doubleKey">1061-4036:2013:Lambert J:meta:analysis:of</idno><idno type="wicri:Area/Main/Merge">000D47</idno><idno type="wicri:Area/Main/Curation">000D36</idno><idno type="wicri:Area/Main/Exploration">000D36</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer’s disease</title><author><name sortKey="Lambert, Jean Charles" sort="Lambert, Jean Charles" uniqKey="Lambert J" first="Jean-Charles" last="Lambert">Jean-Charles Lambert</name><affiliation wicri:level="3"><nlm:aff id="A1">INSERM, U744, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U744, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A2">Université Lille 2, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Université Lille 2, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement><settlement type="city">Lille</settlement></placeName><orgName type="university">Université Lille 2</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A3">Institut Pasteur de Lille, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur de Lille, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Ibrahim Verbaas, Carla A" sort="Ibrahim Verbaas, Carla A" uniqKey="Ibrahim Verbaas C" first="Carla A" last="Ibrahim-Verbaas">Carla A. Ibrahim-Verbaas</name><affiliation wicri:level="3"><nlm:aff id="A4">Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Neurology, Erasmus MC University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Harold, Denise" sort="Harold, Denise" uniqKey="Harold D" first="Denise" last="Harold">Denise Harold</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Naj, Adam C" sort="Naj, Adam C" uniqKey="Naj A" first="Adam C" last="Naj">Adam C. Naj</name><affiliation wicri:level="2"><nlm:aff id="A7">Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A8">Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Sims, Rebecca" sort="Sims, Rebecca" uniqKey="Sims R" first="Rebecca" last="Sims">Rebecca Sims</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Bellenguez, Celine" sort="Bellenguez, Celine" uniqKey="Bellenguez C" first="Céline" last="Bellenguez">Céline Bellenguez</name><affiliation wicri:level="3"><nlm:aff id="A1">INSERM, U744, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U744, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A2">Université Lille 2, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Université Lille 2, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement><settlement type="city">Lille</settlement></placeName><orgName type="university">Université Lille 2</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A3">Institut Pasteur de Lille, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur de Lille, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Jun, Gyungah" sort="Jun, Gyungah" uniqKey="Jun G" first="Gyungah" last="Jun">Gyungah Jun</name><affiliation wicri:level="2"><nlm:aff id="A9">Department of Medicine (Biomedical Genetics), Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine (Biomedical Genetics), Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A10">Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A11">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Destefano, Anita L" sort="Destefano, Anita L" uniqKey="Destefano A" first="Anita L" last="Destefano">Anita L. Destefano</name><affiliation wicri:level="2"><nlm:aff id="A11">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Bis, Joshua C" sort="Bis, Joshua C" uniqKey="Bis J" first="Joshua C" last="Bis">Joshua C. Bis</name><affiliation wicri:level="4"><nlm:aff id="A12">Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Beecham, Gary W" sort="Beecham, Gary W" uniqKey="Beecham G" first="Gary W" last="Beecham">Gary W. Beecham</name><affiliation wicri:level="2"><nlm:aff id="A13">John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A14">Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Grenier Boley, Benjamin" sort="Grenier Boley, Benjamin" uniqKey="Grenier Boley B" first="Benjamin" last="Grenier-Boley">Benjamin Grenier-Boley</name><affiliation wicri:level="3"><nlm:aff id="A1">INSERM, U744, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U744, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A2">Université Lille 2, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Université Lille 2, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement><settlement type="city">Lille</settlement></placeName><orgName type="university">Université Lille 2</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A3">Institut Pasteur de Lille, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur de Lille, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Russo, Giancarlo" sort="Russo, Giancarlo" uniqKey="Russo G" first="Giancarlo" last="Russo">Giancarlo Russo</name><affiliation wicri:level="4"><nlm:aff id="A15">Functional Genomics Center Zurich, Eidgenössische Technische Hochschule (ETH)/University of Zurich, Zurich, Switzerland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suisse</country><wicri:regionArea>Functional Genomics Center Zurich, Eidgenössische Technische Hochschule (ETH)/University of Zurich, Zurich</wicri:regionArea><orgName type="university">Université de Zurich</orgName><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region></placeName></affiliation></author><author><name sortKey="Thornton Wells, Tricia A" sort="Thornton Wells, Tricia A" uniqKey="Thornton Wells T" first="Tricia A" last="Thornton-Wells">Tricia A. Thornton-Wells</name><affiliation wicri:level="2"><nlm:aff id="A16">Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Jones, Nicola" sort="Jones, Nicola" uniqKey="Jones N" first="Nicola" last="Jones">Nicola Jones</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Smith, Albert V" sort="Smith, Albert V" uniqKey="Smith A" first="Albert V" last="Smith">Albert V. Smith</name><affiliation wicri:level="1"><nlm:aff id="A17">Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A18">Icelandic Heart Association, Kopavogur, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation></author><author><name sortKey="Chouraki, Vincent" sort="Chouraki, Vincent" uniqKey="Chouraki V" first="Vincent" last="Chouraki">Vincent Chouraki</name><affiliation wicri:level="3"><nlm:aff id="A1">INSERM, U744, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U744, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A2">Université Lille 2, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Université Lille 2, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement><settlement type="city">Lille</settlement></placeName><orgName type="university">Université Lille 2</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A3">Institut Pasteur de Lille, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur de Lille, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Thomas, Charlene" sort="Thomas, Charlene" uniqKey="Thomas C" first="Charlene" last="Thomas">Charlene Thomas</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Ikram, M Arfan" sort="Ikram, M Arfan" uniqKey="Ikram M" first="M Arfan" last="Ikram">M Arfan Ikram</name><affiliation wicri:level="3"><nlm:aff id="A4">Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Neurology, Erasmus MC University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A19">Department of Radiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Radiology, Erasmus MC University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A20">Netherlands Consortium for Healthy Aging, Leiden, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherlands Consortium for Healthy Aging, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Zelenika, Diana" sort="Zelenika, Diana" uniqKey="Zelenika D" first="Diana" last="Zelenika">Diana Zelenika</name><affiliation wicri:level="3"><nlm:aff id="A21">Centre National de Génotypage, Institut Génomique, Commissariat à l’Energie Atomique, Evry, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre National de Génotypage, Institut Génomique, Commissariat à l’Energie Atomique, Evry</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Évry (Essonne)</settlement></placeName></affiliation></author><author><name sortKey="Vardarajan, Badri N" sort="Vardarajan, Badri N" uniqKey="Vardarajan B" first="Badri N" last="Vardarajan">Badri N. Vardarajan</name><affiliation wicri:level="2"><nlm:aff id="A9">Department of Medicine (Biomedical Genetics), Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine (Biomedical Genetics), Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Kamatani, Yoichiro" sort="Kamatani, Yoichiro" uniqKey="Kamatani Y" first="Yoichiro" last="Kamatani">Yoichiro Kamatani</name><affiliation wicri:level="3"><nlm:aff id="A22">Fondation Jean Dausset, Centre d’Etude du Polymorphisme Humain (CEPH), Paris, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Fondation Jean Dausset, Centre d’Etude du Polymorphisme Humain (CEPH), Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Lin, Chiao Feng" sort="Lin, Chiao Feng" uniqKey="Lin C" first="Chiao-Feng" last="Lin">Chiao-Feng Lin</name><affiliation wicri:level="2"><nlm:aff id="A23">Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Gerrish, Amy" sort="Gerrish, Amy" uniqKey="Gerrish A" first="Amy" last="Gerrish">Amy Gerrish</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Schmidt, Helena" sort="Schmidt, Helena" uniqKey="Schmidt H" first="Helena" last="Schmidt">Helena Schmidt</name><affiliation wicri:level="1"><nlm:aff id="A24">Institute for Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Autriche</country><wicri:regionArea>Institute for Molecular Biology and Biochemistry, Medical University of Graz, Graz</wicri:regionArea><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Kunkle, Brian" sort="Kunkle, Brian" uniqKey="Kunkle B" first="Brian" last="Kunkle">Brian Kunkle</name><affiliation wicri:level="2"><nlm:aff id="A13">John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Dunstan, Melanie L" sort="Dunstan, Melanie L" uniqKey="Dunstan M" first="Melanie L" last="Dunstan">Melanie L. Dunstan</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Ruiz, Agustin" sort="Ruiz, Agustin" uniqKey="Ruiz A" first="Agustin" last="Ruiz">Agustin Ruiz</name><affiliation wicri:level="3"><nlm:aff id="A25">Memory Clinic of Fundació Alzheimer Centre Educacional (ACE). Institut Català de Neurociències Aplicades, Barcelona, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Memory Clinic of Fundació Alzheimer Centre Educacional (ACE). Institut Català de Neurociències Aplicades, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Bihoreau, Marie Therese" sort="Bihoreau, Marie Therese" uniqKey="Bihoreau M" first="Marie-Thérèse" last="Bihoreau">Marie-Thérèse Bihoreau</name><affiliation wicri:level="3"><nlm:aff id="A21">Centre National de Génotypage, Institut Génomique, Commissariat à l’Energie Atomique, Evry, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre National de Génotypage, Institut Génomique, Commissariat à l’Energie Atomique, Evry</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Évry (Essonne)</settlement></placeName></affiliation></author><author><name sortKey="Choi, Seung Hoan" sort="Choi, Seung Hoan" uniqKey="Choi S" first="Seung-Hoan" last="Choi">Seung-Hoan Choi</name><affiliation wicri:level="2"><nlm:aff id="A11">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Reitz, Christiane" sort="Reitz, Christiane" uniqKey="Reitz C" first="Christiane" last="Reitz">Christiane Reitz</name><affiliation wicri:level="4"><nlm:aff id="A26">Taub Institute on Alzheimer’s Disease and the Aging Brain, Department of Neurology, Columbia University, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Taub Institute on Alzheimer’s Disease and the Aging Brain, Department of Neurology, Columbia University, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A27">Gertrude H. Sergievsky Center, Department of Neurology, Columbia University, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Gertrude H. Sergievsky Center, Department of Neurology, Columbia University, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Pasquier, Florence" sort="Pasquier, Florence" uniqKey="Pasquier F" first="Florence" last="Pasquier">Florence Pasquier</name><affiliation wicri:level="4"><nlm:aff id="A2">Université Lille 2, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Université Lille 2, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement><settlement type="city">Lille</settlement></placeName><orgName type="university">Université Lille 2</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A28">Centre National de Reference pour les Malades Alzheimer Jeunes (CNR-MAJ), Centre Hospitalier Régional Universitaire de Lille, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre National de Reference pour les Malades Alzheimer Jeunes (CNR-MAJ), Centre Hospitalier Régional Universitaire de Lille, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Hollingworth, Paul" sort="Hollingworth, Paul" uniqKey="Hollingworth P" first="Paul" last="Hollingworth">Paul Hollingworth</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Ramirez, Alfredo" sort="Ramirez, Alfredo" uniqKey="Ramirez A" first="Alfredo" last="Ramirez">Alfredo Ramirez</name><affiliation wicri:level="3"><nlm:aff id="A29">Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Psychiatry and Psychotherapy, University of Bonn, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A30">Institute of Human Genetics, University of Bonn, Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Human Genetics, University of Bonn, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation></author><author><name sortKey="Hanon, Olivier" sort="Hanon, Olivier" uniqKey="Hanon O" first="Olivier" last="Hanon">Olivier Hanon</name><affiliation wicri:level="3"><nlm:aff id="A31">University Paris Descartes, Sorbonne Paris V, Broca Hospital, Geriatrics Department, Paris, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>University Paris Descartes, Sorbonne Paris V, Broca Hospital, Geriatrics Department, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Fitzpatrick, Annette L" sort="Fitzpatrick, Annette L" uniqKey="Fitzpatrick A" first="Annette L" last="Fitzpatrick">Annette L. Fitzpatrick</name><affiliation wicri:level="4"><nlm:aff id="A12">Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A32">Department of Epidemiology, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A33">Department of Global Health, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Global Health, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Buxbaum, Joseph D" sort="Buxbaum, Joseph D" uniqKey="Buxbaum J" first="Joseph D" last="Buxbaum">Joseph D. Buxbaum</name><affiliation wicri:level="2"><nlm:aff id="A34">Department of Neuroscience, Mount Sinai School of Medicine, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Neuroscience, Mount Sinai School of Medicine, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A35">Department of Psychiatry, Mount Sinai School of Medicine, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Psychiatry, Mount Sinai School of Medicine, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A36">Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Campion, Dominique" sort="Campion, Dominique" uniqKey="Campion D" first="Dominique" last="Campion">Dominique Campion</name><affiliation wicri:level="3"><nlm:aff id="A37">CNR-MAJ, INSERM, U1079, Rouen University Hospital, Rouen, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNR-MAJ, INSERM, U1079, Rouen University Hospital, Rouen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Haute-Normandie</region><settlement type="city">Rouen</settlement></placeName></affiliation></author><author><name sortKey="Crane, Paul K" sort="Crane, Paul K" uniqKey="Crane P" first="Paul K" last="Crane">Paul K. Crane</name><affiliation wicri:level="4"><nlm:aff id="A38">Department of Medicine, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Baldwin, Clinton" sort="Baldwin, Clinton" uniqKey="Baldwin C" first="Clinton" last="Baldwin">Clinton Baldwin</name><affiliation wicri:level="2"><nlm:aff id="A9">Department of Medicine (Biomedical Genetics), Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine (Biomedical Genetics), Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Becker, Tim" sort="Becker, Tim" uniqKey="Becker T" first="Tim" last="Becker">Tim Becker</name><affiliation wicri:level="3"><nlm:aff id="A39">German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>German Center for Neurodegenerative Diseases (DZNE), Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A40">Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation wicri:level="1"><nlm:aff id="A17">Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A18">Icelandic Heart Association, Kopavogur, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation></author><author><name sortKey="Cruchaga, Carlos" sort="Cruchaga, Carlos" uniqKey="Cruchaga C" first="Carlos" last="Cruchaga">Carlos Cruchaga</name><affiliation wicri:level="4"><nlm:aff id="A41">Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A42">Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, Missouri, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation></author><author><name sortKey="Craig, David" sort="Craig, David" uniqKey="Craig D" first="David" last="Craig">David Craig</name><affiliation wicri:level="1"><nlm:aff id="A43">Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast</wicri:regionArea><wicri:noRegion>Belfast</wicri:noRegion></affiliation></author><author><name sortKey="Amin, Najaf" sort="Amin, Najaf" uniqKey="Amin N" first="Najaf" last="Amin">Najaf Amin</name><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Berr, Claudine" sort="Berr, Claudine" uniqKey="Berr C" first="Claudine" last="Berr">Claudine Berr</name><affiliation wicri:level="3"><nlm:aff id="A44">INSERM, U1061, Faculty of Medicine, Hôpital La Colombière, Montpellier, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U1061, Faculty of Medicine, Hôpital La Colombière, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Lopez, Oscar L" sort="Lopez, Oscar L" uniqKey="Lopez O" first="Oscar L" last="Lopez">Oscar L. Lopez</name><affiliation wicri:level="2"><nlm:aff id="A45">Departments of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Departments of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="De Jager, Philip L" sort="De Jager, Philip L" uniqKey="De Jager P" first="Philip L" last="De Jager">Philip L. De Jager</name><affiliation wicri:level="2"><nlm:aff id="A46">Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Department of Neurology & Psychiatry, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Department of Neurology & Psychiatry, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A47">Program in Medical and Population Genetics, Broad Institute, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Program in Medical and Population Genetics, Broad Institute, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Deramecourt, Vincent" sort="Deramecourt, Vincent" uniqKey="Deramecourt V" first="Vincent" last="Deramecourt">Vincent Deramecourt</name><affiliation wicri:level="4"><nlm:aff id="A2">Université Lille 2, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Université Lille 2, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement><settlement type="city">Lille</settlement></placeName><orgName type="university">Université Lille 2</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A28">Centre National de Reference pour les Malades Alzheimer Jeunes (CNR-MAJ), Centre Hospitalier Régional Universitaire de Lille, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre National de Reference pour les Malades Alzheimer Jeunes (CNR-MAJ), Centre Hospitalier Régional Universitaire de Lille, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Johnston, Janet A" sort="Johnston, Janet A" uniqKey="Johnston J" first="Janet A" last="Johnston">Janet A. Johnston</name><affiliation wicri:level="1"><nlm:aff id="A43">Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast</wicri:regionArea><wicri:noRegion>Belfast</wicri:noRegion></affiliation></author><author><name sortKey="Evans, Denis" sort="Evans, Denis" uniqKey="Evans D" first="Denis" last="Evans">Denis Evans</name><affiliation wicri:level="2"><nlm:aff id="A48">Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Lovestone, Simon" sort="Lovestone, Simon" uniqKey="Lovestone S" first="Simon" last="Lovestone">Simon Lovestone</name><affiliation wicri:level="3"><nlm:aff id="A49">Institute of Psychiatry, King’s College London, Denmark Hill, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychiatry, King’s College London, Denmark Hill, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Letenneur, Luc" sort="Letenneur, Luc" uniqKey="Letenneur L" first="Luc" last="Letenneur">Luc Letenneur</name><affiliation wicri:level="3"><nlm:aff id="A50">INSERM, U897, Victor Segalen University, Bordeaux, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U897, Victor Segalen University, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Mor N, Francisco J" sort="Mor N, Francisco J" uniqKey="Mor N F" first="Francisco J" last="Mor N">Francisco J. Mor N</name><affiliation wicri:level="1"><nlm:aff id="A51">Departamento de Genómica Estructural, Neocodex, Seville, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Departamento de Genómica Estructural, Neocodex, Seville</wicri:regionArea><wicri:noRegion>Seville</wicri:noRegion></affiliation></author><author><name sortKey="Rubinsztein, David C" sort="Rubinsztein, David C" uniqKey="Rubinsztein D" first="David C" last="Rubinsztein">David C. Rubinsztein</name><affiliation wicri:level="4"><nlm:aff id="A52">Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Cambridge Institute for Medical Research, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Eiriksdottir, Gudny" sort="Eiriksdottir, Gudny" uniqKey="Eiriksdottir G" first="Gudny" last="Eiriksdottir">Gudny Eiriksdottir</name><affiliation wicri:level="1"><nlm:aff id="A18">Icelandic Heart Association, Kopavogur, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Icelandic Heart Association, Kopavogur</wicri:regionArea><wicri:noRegion>Kopavogur</wicri:noRegion></affiliation></author><author><name sortKey="Sleegers, Kristel" sort="Sleegers, Kristel" uniqKey="Sleegers K" first="Kristel" last="Sleegers">Kristel Sleegers</name><affiliation wicri:level="1"><nlm:aff id="A53">Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp, Belgium.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Belgique</country><wicri:regionArea>Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp</wicri:regionArea><wicri:noRegion>Antwerp</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A54">Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Belgique</country><wicri:regionArea>Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp</wicri:regionArea><orgName type="university">Université d'Anvers</orgName><placeName><settlement type="city">Anvers</settlement><region>Région flamande</region><region type="district" nuts="2">Province d'Anvers</region></placeName></affiliation></author><author><name sortKey="Goate, Alison M" sort="Goate, Alison M" uniqKey="Goate A" first="Alison M" last="Goate">Alison M. Goate</name><affiliation wicri:level="4"><nlm:aff id="A41">Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Psychiatry, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A42">Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, Missouri, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, Missouri</wicri:regionArea><placeName><region type="state">Missouri (État)</region><settlement type="city">Saint-Louis (Missouri)</settlement></placeName><orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName></affiliation></author><author><name sortKey="Fievet, Nathalie" sort="Fievet, Nathalie" uniqKey="Fievet N" first="Nathalie" last="Fiévet">Nathalie Fiévet</name><affiliation wicri:level="3"><nlm:aff id="A1">INSERM, U744, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U744, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A3">Institut Pasteur de Lille, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur de Lille, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Huentelman, Matthew J" sort="Huentelman, Matthew J" uniqKey="Huentelman M" first="Matthew J" last="Huentelman">Matthew J. Huentelman</name><affiliation wicri:level="2"><nlm:aff id="A55">Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Arizona, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Arizona</wicri:regionArea><placeName><region type="state">Arizona</region></placeName></affiliation></author><author><name sortKey="Gill, Michael" sort="Gill, Michael" uniqKey="Gill M" first="Michael" last="Gill">Michael Gill</name><affiliation wicri:level="1"><nlm:aff id="A56">Mercer’s Institute for Research on Aging, St. James Hospital and Trinity College, Dublin, Ireland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Irlande (pays)</country><wicri:regionArea>Mercer’s Institute for Research on Aging, St. James Hospital and Trinity College, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Brown, Kristelle" sort="Brown, Kristelle" uniqKey="Brown K" first="Kristelle" last="Brown">Kristelle Brown</name><affiliation wicri:level="4"><nlm:aff id="A57">Institute of Genetics, Queen’s Medical Centre, University of Nottingham, Nottingham, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Genetics, Queen’s Medical Centre, University of Nottingham, Nottingham</wicri:regionArea><orgName type="university">Université de Nottingham</orgName><placeName><settlement type="city">Nottingham</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Nottinghamshire</region></placeName></affiliation></author><author><name sortKey="Kamboh, M Ilyas" sort="Kamboh, M Ilyas" uniqKey="Kamboh M" first="M Ilyas" last="Kamboh">M Ilyas Kamboh</name><affiliation wicri:level="4"><nlm:aff id="A58">Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Human Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region><settlement type="city">Pittsburgh</settlement></placeName><orgName type="university">Université de Pittsburgh</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A59">Alzheimer’s Disease Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Alzheimer’s Disease Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region><settlement type="city">Pittsburgh</settlement></placeName><orgName type="university">Université de Pittsburgh</orgName></affiliation></author><author><name sortKey="Keller, Lina" sort="Keller, Lina" uniqKey="Keller L" first="Lina" last="Keller">Lina Keller</name><affiliation wicri:level="3"><nlm:aff id="A60">Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Barberger Gateau, Pascale" sort="Barberger Gateau, Pascale" uniqKey="Barberger Gateau P" first="Pascale" last="Barberger-Gateau">Pascale Barberger-Gateau</name><affiliation wicri:level="3"><nlm:aff id="A50">INSERM, U897, Victor Segalen University, Bordeaux, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U897, Victor Segalen University, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Mcguinness, Bernadette" sort="Mcguinness, Bernadette" uniqKey="Mcguinness B" first="Bernadette" last="Mcguinness">Bernadette Mcguinness</name><affiliation wicri:level="1"><nlm:aff id="A43">Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast</wicri:regionArea><wicri:noRegion>Belfast</wicri:noRegion></affiliation></author><author><name sortKey="Larson, Eric B" sort="Larson, Eric B" uniqKey="Larson E" first="Eric B" last="Larson">Eric B. Larson</name><affiliation wicri:level="4"><nlm:aff id="A38">Department of Medicine, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="2"><nlm:aff id="A61">Group Health Research Institute, Group Health, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Group Health Research Institute, Group Health, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Green, Robert" sort="Green, Robert" uniqKey="Green R" first="Robert" last="Green">Robert Green</name><affiliation wicri:level="2"><nlm:aff id="A62">Department of Medicine and Partners Center for Personalized Genetic Medicine, Division of Genetics, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine and Partners Center for Personalized Genetic Medicine, Division of Genetics, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Myers, Amanda J" sort="Myers, Amanda J" uniqKey="Myers A" first="Amanda J" last="Myers">Amanda J. Myers</name><affiliation wicri:level="2"><nlm:aff id="A63">Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Dufouil, Carole" sort="Dufouil, Carole" uniqKey="Dufouil C" first="Carole" last="Dufouil">Carole Dufouil</name><affiliation wicri:level="3"><nlm:aff id="A50">INSERM, U897, Victor Segalen University, Bordeaux, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U897, Victor Segalen University, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Todd, Stephen" sort="Todd, Stephen" uniqKey="Todd S" first="Stephen" last="Todd">Stephen Todd</name><affiliation wicri:level="1"><nlm:aff id="A43">Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast</wicri:regionArea><wicri:noRegion>Belfast</wicri:noRegion></affiliation></author><author><name sortKey="Wallon, David" sort="Wallon, David" uniqKey="Wallon D" first="David" last="Wallon">David Wallon</name><affiliation wicri:level="3"><nlm:aff id="A37">CNR-MAJ, INSERM, U1079, Rouen University Hospital, Rouen, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNR-MAJ, INSERM, U1079, Rouen University Hospital, Rouen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Haute-Normandie</region><settlement type="city">Rouen</settlement></placeName></affiliation></author><author><name sortKey="Love, Seth" sort="Love, Seth" uniqKey="Love S" first="Seth" last="Love">Seth Love</name><affiliation wicri:level="1"><nlm:aff id="A64">University of Bristol Institute of Clinical Neurosciences, School of Clinical Sciences, Frenchay Hospital, Bristol, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>University of Bristol Institute of Clinical Neurosciences, School of Clinical Sciences, Frenchay Hospital, Bristol</wicri:regionArea><wicri:noRegion>Bristol</wicri:noRegion></affiliation></author><author><name sortKey="Rogaeva, Ekaterina" sort="Rogaeva, Ekaterina" uniqKey="Rogaeva E" first="Ekaterina" last="Rogaeva">Ekaterina Rogaeva</name><affiliation wicri:level="4"><nlm:aff id="A65">Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Canada</country><wicri:regionArea>Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation></author><author><name sortKey="Gallacher, John" sort="Gallacher, John" uniqKey="Gallacher J" first="John" last="Gallacher">John Gallacher</name><affiliation wicri:level="1"><nlm:aff id="A66">Institute of Primary Care and Public Health, Cardiff University, Neuadd Meirionnydd, University Hospital of Wales, Heath Park, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Primary Care and Public Health, Cardiff University, Neuadd Meirionnydd, University Hospital of Wales, Heath Park, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="St George Hyslop, Peter" sort="St George Hyslop, Peter" uniqKey="St George Hyslop P" first="Peter" last="St George-Hyslop">Peter St George-Hyslop</name><affiliation wicri:level="4"><nlm:aff id="A52">Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Cambridge Institute for Medical Research, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A65">Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Canada</country><wicri:regionArea>Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario</wicri:regionArea><orgName type="university">Université de Toronto</orgName><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A67">Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Department of Clinical Neurosciences, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Clarimon, Jordi" sort="Clarimon, Jordi" uniqKey="Clarimon J" first="Jordi" last="Clarimon">Jordi Clarimon</name><affiliation wicri:level="4"><nlm:aff id="A68">Neurology Department. Biomedical Research Institute Sant Pau (IIB Sant Pau). Sant Pau Hospital. Universitat Autònoma de Barcelona, Barcelona, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Neurology Department. Biomedical Research Institute Sant Pau (IIB Sant Pau). Sant Pau Hospital. Universitat Autònoma de Barcelona, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region><settlement type="city">Barcelone</settlement></placeName><orgName type="university">Université autonome de Barcelone</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A69">Center for Networker Biomedical Research in Neurodegenerative Diseases (CIBERNED), Barcelona, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Center for Networker Biomedical Research in Neurodegenerative Diseases (CIBERNED), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Lleo, Alberto" sort="Lleo, Alberto" uniqKey="Lleo A" first="Alberto" last="Lleo">Alberto Lleo</name><affiliation wicri:level="4"><nlm:aff id="A68">Neurology Department. Biomedical Research Institute Sant Pau (IIB Sant Pau). Sant Pau Hospital. Universitat Autònoma de Barcelona, Barcelona, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Neurology Department. Biomedical Research Institute Sant Pau (IIB Sant Pau). Sant Pau Hospital. Universitat Autònoma de Barcelona, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region><settlement type="city">Barcelone</settlement></placeName><orgName type="university">Université autonome de Barcelone</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A69">Center for Networker Biomedical Research in Neurodegenerative Diseases (CIBERNED), Barcelona, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Center for Networker Biomedical Research in Neurodegenerative Diseases (CIBERNED), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Bayer, Anthony" sort="Bayer, Anthony" uniqKey="Bayer A" first="Anthony" last="Bayer">Anthony Bayer</name><affiliation wicri:level="1"><nlm:aff id="A66">Institute of Primary Care and Public Health, Cardiff University, Neuadd Meirionnydd, University Hospital of Wales, Heath Park, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Primary Care and Public Health, Cardiff University, Neuadd Meirionnydd, University Hospital of Wales, Heath Park, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Tsuang, Debby W" sort="Tsuang, Debby W" uniqKey="Tsuang D" first="Debby W" last="Tsuang">Debby W. Tsuang</name><affiliation wicri:level="2"><nlm:aff id="A70">Geriatric Research, Education and Clinical Center (GRECC), Veteran Administration Puget Sound Health Care System (VAPSHCS), Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Geriatric Research, Education and Clinical Center (GRECC), Veteran Administration Puget Sound Health Care System (VAPSHCS), Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation></author><author><name sortKey="Yu, Lei" sort="Yu, Lei" uniqKey="Yu L" first="Lei" last="Yu">Lei Yu</name><affiliation wicri:level="2"><nlm:aff id="A71">Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Tsolaki, Magda" sort="Tsolaki, Magda" uniqKey="Tsolaki M" first="Magda" last="Tsolaki">Magda Tsolaki</name><affiliation wicri:level="1"><nlm:aff id="A72">Department of Neurology, Aristotle University of Thessaloniki, Thessaloniki, Greece.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Grèce</country><wicri:regionArea>Department of Neurology, Aristotle University of Thessaloniki, Thessaloniki</wicri:regionArea><wicri:noRegion>Thessaloniki</wicri:noRegion></affiliation></author><author><name sortKey="Bossu, Paola" sort="Bossu, Paola" uniqKey="Bossu P" first="Paola" last="Bossù">Paola Bossù</name><affiliation wicri:level="3"><nlm:aff id="A73">Clinical and Behavioral Neurology, Fondazione Santa Lucia, Rome, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Clinical and Behavioral Neurology, Fondazione Santa Lucia, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Spalletta, Gianfranco" sort="Spalletta, Gianfranco" uniqKey="Spalletta G" first="Gianfranco" last="Spalletta">Gianfranco Spalletta</name><affiliation wicri:level="3"><nlm:aff id="A73">Clinical and Behavioral Neurology, Fondazione Santa Lucia, Rome, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Clinical and Behavioral Neurology, Fondazione Santa Lucia, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author><author><name sortKey="Proitsi, Petroula" sort="Proitsi, Petroula" uniqKey="Proitsi P" first="Petroula" last="Proitsi">Petroula Proitsi</name><affiliation wicri:level="3"><nlm:aff id="A49">Institute of Psychiatry, King’s College London, Denmark Hill, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychiatry, King’s College London, Denmark Hill, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Collinge, John" sort="Collinge, John" uniqKey="Collinge J" first="John" last="Collinge">John Collinge</name><affiliation wicri:level="3"><nlm:aff id="A74">MRC Prion Unit, Department of Neurodegenerative Disease, University College London Institute of Neurology, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Prion Unit, Department of Neurodegenerative Disease, University College London Institute of Neurology, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Sorbi, Sandro" sort="Sorbi, Sandro" uniqKey="Sorbi S" first="Sandro" last="Sorbi">Sandro Sorbi</name><affiliation wicri:level="1"><nlm:aff id="A75">NEUROFARBA (Department of Neuroscience, Psychology, Drug Research and Child Health), University of Florence, Florence, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>NEUROFARBA (Department of Neuroscience, Psychology, Drug Research and Child Health), University of Florence, Florence</wicri:regionArea><wicri:noRegion>Florence</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A76">Centro di Ricerca, Trasferimento e Alta Formazione DENOTHE, University of Florence, Florence, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Centro di Ricerca, Trasferimento e Alta Formazione DENOTHE, University of Florence, Florence</wicri:regionArea><wicri:noRegion>Florence</wicri:noRegion></affiliation></author><author><name sortKey="Sanchez Garcia, Florentino" sort="Sanchez Garcia, Florentino" uniqKey="Sanchez Garcia F" first="Florentino" last="Sanchez-Garcia">Florentino Sanchez-Garcia</name><affiliation wicri:level="1"><nlm:aff id="A77">Department of Immunology, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Immunology, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria</wicri:regionArea><wicri:noRegion>Las Palmas de Gran Canaria</wicri:noRegion></affiliation></author><author><name sortKey="Fox, Nick C" sort="Fox, Nick C" uniqKey="Fox N" first="Nick C" last="Fox">Nick C. Fox</name><affiliation wicri:level="3"><nlm:aff id="A78">Dementia Research Centre, Department of Neurodegenerative Disease, University College London Institute of Neurology, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Dementia Research Centre, Department of Neurodegenerative Disease, University College London Institute of Neurology, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Hardy, John" sort="Hardy, John" uniqKey="Hardy J" first="John" last="Hardy">John Hardy</name><affiliation wicri:level="3"><nlm:aff id="A79">Department of Molecular Neuroscience, Institute of Neurology, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Department of Molecular Neuroscience, Institute of Neurology, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A80">Reta Lilla Weston Laboratories, Institute of Neurology, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Reta Lilla Weston Laboratories, Institute of Neurology, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Deniz Naranjo, Maria Candida" sort="Deniz Naranjo, Maria Candida" uniqKey="Deniz Naranjo M" first="Maria Candida" last="Deniz Naranjo">Maria Candida Deniz Naranjo</name><affiliation wicri:level="1"><nlm:aff id="A77">Department of Immunology, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Department of Immunology, Hospital Universitario Dr. Negrin, Las Palmas de Gran Canaria</wicri:regionArea><wicri:noRegion>Las Palmas de Gran Canaria</wicri:noRegion></affiliation></author><author><name sortKey="Bosco, Paolo" sort="Bosco, Paolo" uniqKey="Bosco P" first="Paolo" last="Bosco">Paolo Bosco</name><affiliation wicri:level="1"><nlm:aff id="A81">Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Associazione Oasi Maria Santissima Srl, Troina, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Associazione Oasi Maria Santissima Srl, Troina</wicri:regionArea><wicri:noRegion>Troina</wicri:noRegion></affiliation></author><author><name sortKey="Clarke, Robert" sort="Clarke, Robert" uniqKey="Clarke R" first="Robert" last="Clarke">Robert Clarke</name><affiliation wicri:level="4"><nlm:aff id="A82">Oxford Healthy Aging Project (OHAP), Clinical Trial Service Unit, University of Oxford, Oxford, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Oxford Healthy Aging Project (OHAP), Clinical Trial Service Unit, University of Oxford, Oxford</wicri:regionArea><placeName><settlement type="city">Oxford</settlement><region type="country">Angleterre</region><region type="comté" nuts="2">Oxfordshire</region><settlement type="city">Oxford</settlement></placeName><orgName type="university">Université d'Oxford</orgName></affiliation></author><author><name sortKey="Brayne, Carol" sort="Brayne, Carol" uniqKey="Brayne C" first="Carol" last="Brayne">Carol Brayne</name><affiliation wicri:level="4"><nlm:aff id="A83">Institute of Public Health, University of Cambridge, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Public Health, University of Cambridge, Cambridge</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Galimberti, Daniela" sort="Galimberti, Daniela" uniqKey="Galimberti D" first="Daniela" last="Galimberti">Daniela Galimberti</name><affiliation wicri:level="3"><nlm:aff id="A84">University of Milan, Fondazione Cà Granda, IRCCS Ospedale Policlinico, Milan, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>University of Milan, Fondazione Cà Granda, IRCCS Ospedale Policlinico, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Mancuso, Michelangelo" sort="Mancuso, Michelangelo" uniqKey="Mancuso M" first="Michelangelo" last="Mancuso">Michelangelo Mancuso</name><affiliation wicri:level="4"><nlm:aff id="A85">Neurological Clinic, University of Pisa, Pisa, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Neurological Clinic, University of Pisa, Pisa</wicri:regionArea><placeName><settlement type="city">Pise</settlement><region nuts="2">Toscane</region><settlement type="city">Pise</settlement></placeName><orgName type="university">Université de Pise</orgName></affiliation></author><author><name sortKey="Matthews, Fiona" sort="Matthews, Fiona" uniqKey="Matthews F" first="Fiona" last="Matthews">Fiona Matthews</name><affiliation wicri:level="1"><nlm:aff id="A86">MRC Biostatistics Unit, Cambridge, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Biostatistics Unit, Cambridge</wicri:regionArea><wicri:noRegion>Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Moebus, Susanne" sort="Moebus, Susanne" uniqKey="Moebus S" first="Susanne" last="Moebus">Susanne Moebus</name><affiliation wicri:level="1"><nlm:aff id="A88">Urban Epidemiology, Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Urban Epidemiology, Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University Duisburg-Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Mecocci, Patrizia" sort="Mecocci, Patrizia" uniqKey="Mecocci P" first="Patrizia" last="Mecocci">Patrizia Mecocci</name><affiliation wicri:level="1"><nlm:aff id="A89">Section of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Section of Gerontology and Geriatrics, Department of Clinical and Experimental Medicine, University of Perugia, Perugia</wicri:regionArea><wicri:noRegion>Perugia</wicri:noRegion></affiliation></author><author><name sortKey="Zompo, Maria Del" sort="Zompo, Maria Del" uniqKey="Zompo M" first="Maria Del" last="Zompo">Maria Del Zompo</name><affiliation wicri:level="1"><nlm:aff id="A90">Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, Cagliari</wicri:regionArea><wicri:noRegion>Cagliari</wicri:noRegion></affiliation></author><author><name sortKey="Maier, Wolfgang" sort="Maier, Wolfgang" uniqKey="Maier W" first="Wolfgang" last="Maier">Wolfgang Maier</name><affiliation wicri:level="3"><nlm:aff id="A29">Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Psychiatry and Psychotherapy, University of Bonn, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A39">German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>German Center for Neurodegenerative Diseases (DZNE), Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation></author><author><name sortKey="Hampel, Harald" sort="Hampel, Harald" uniqKey="Hampel H" first="Harald" last="Hampel">Harald Hampel</name><affiliation wicri:level="3"><nlm:aff id="A91">Department of Psychiatry, University of Frankfurt, Frankfurt am Main, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Psychiatry, University of Frankfurt, Frankfurt am Main</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A92">Department of Psychiatry, Ludwig Maximilians University, Munich, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Psychiatry, Ludwig Maximilians University, Munich</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Munich</settlement><settlement type="city">Munich</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Pilotto, Alberto" sort="Pilotto, Alberto" uniqKey="Pilotto A" first="Alberto" last="Pilotto">Alberto Pilotto</name><affiliation wicri:level="1"><nlm:aff id="A93">Gerontology and Geriatrics Research Laboratory, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Gerontology and Geriatrics Research Laboratory, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo</wicri:regionArea><wicri:noRegion>San Giovanni Rotondo</wicri:noRegion></affiliation></author><author><name sortKey="Bullido, Maria" sort="Bullido, Maria" uniqKey="Bullido M" first="Maria" last="Bullido">Maria Bullido</name><affiliation wicri:level="4"><nlm:aff id="A94">Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas–Universidad Autónoma de Madrid, Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas–Universidad Autónoma de Madrid, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region><settlement type="city">Madrid</settlement></placeName><orgName type="university">Université autonome de Madrid</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A95">Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A96">Instituto de Investigación Sanitaria Hospital la Paz (IdIPaz), Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Instituto de Investigación Sanitaria Hospital la Paz (IdIPaz), Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Panza, Francesco" sort="Panza, Francesco" uniqKey="Panza F" first="Francesco" last="Panza">Francesco Panza</name><affiliation wicri:level="1"><nlm:aff id="A97">Departement of Geriatrics, Center for Aging Brain, University of Bari, Bari, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Departement of Geriatrics, Center for Aging Brain, University of Bari, Bari</wicri:regionArea><wicri:noRegion>Bari</wicri:noRegion></affiliation></author><author><name sortKey="Caffarra, Paolo" sort="Caffarra, Paolo" uniqKey="Caffarra P" first="Paolo" last="Caffarra">Paolo Caffarra</name><affiliation wicri:level="1"><nlm:aff id="A98">Department of Neuroscience, University of Parma, Parma, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Department of Neuroscience, University of Parma, Parma</wicri:regionArea><wicri:noRegion>Parma</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A99">Center for Cognitive Disorders, Azienda Unita Sanitaria Local (AUSL), Parma, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Center for Cognitive Disorders, Azienda Unita Sanitaria Local (AUSL), Parma</wicri:regionArea><wicri:noRegion>Parma</wicri:noRegion></affiliation></author><author><name sortKey="Nacmias, Benedetta" sort="Nacmias, Benedetta" uniqKey="Nacmias B" first="Benedetta" last="Nacmias">Benedetta Nacmias</name><affiliation wicri:level="1"><nlm:aff id="A75">NEUROFARBA (Department of Neuroscience, Psychology, Drug Research and Child Health), University of Florence, Florence, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>NEUROFARBA (Department of Neuroscience, Psychology, Drug Research and Child Health), University of Florence, Florence</wicri:regionArea><wicri:noRegion>Florence</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A76">Centro di Ricerca, Trasferimento e Alta Formazione DENOTHE, University of Florence, Florence, Italy.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Italie</country><wicri:regionArea>Centro di Ricerca, Trasferimento e Alta Formazione DENOTHE, University of Florence, Florence</wicri:regionArea><wicri:noRegion>Florence</wicri:noRegion></affiliation></author><author><name sortKey="Gilbert, John R" sort="Gilbert, John R" uniqKey="Gilbert J" first="John R" last="Gilbert">John R. Gilbert</name><affiliation wicri:level="2"><nlm:aff id="A13">John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A14">Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Mayhaus, Manuel" sort="Mayhaus, Manuel" uniqKey="Mayhaus M" first="Manuel" last="Mayhaus">Manuel Mayhaus</name><affiliation wicri:level="1"><nlm:aff id="A100">Department of Psychiatry, Saarland University Hospital, Homburg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Psychiatry, Saarland University Hospital, Homburg</wicri:regionArea><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion></affiliation></author><author><name sortKey="Lannfelt, Lars" sort="Lannfelt, Lars" uniqKey="Lannfelt L" first="Lars" last="Lannfelt">Lars Lannfelt</name><affiliation wicri:level="4"><nlm:aff id="A101">Department of Public Health/Geriatrics, Uppsala University, Uppsala, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Department of Public Health/Geriatrics, Uppsala University, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Hakonarson, Hakon" sort="Hakonarson, Hakon" uniqKey="Hakonarson H" first="Hakon" last="Hakonarson">Hakon Hakonarson</name><affiliation wicri:level="2"><nlm:aff id="A102">Center for Applied Genomics, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Center for Applied Genomics, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Pichler, Sabrina" sort="Pichler, Sabrina" uniqKey="Pichler S" first="Sabrina" last="Pichler">Sabrina Pichler</name><affiliation wicri:level="1"><nlm:aff id="A100">Department of Psychiatry, Saarland University Hospital, Homburg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Psychiatry, Saarland University Hospital, Homburg</wicri:regionArea><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion></affiliation></author><author><name sortKey="Carrasquillo, Minerva M" sort="Carrasquillo, Minerva M" uniqKey="Carrasquillo M" first="Minerva M" last="Carrasquillo">Minerva M. Carrasquillo</name><affiliation wicri:level="2"><nlm:aff id="A103">Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Neuroscience, Mayo Clinic, Jacksonville, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Ingelsson, Martin" sort="Ingelsson, Martin" uniqKey="Ingelsson M" first="Martin" last="Ingelsson">Martin Ingelsson</name><affiliation wicri:level="4"><nlm:aff id="A101">Department of Public Health/Geriatrics, Uppsala University, Uppsala, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Department of Public Health/Geriatrics, Uppsala University, Uppsala</wicri:regionArea><orgName type="university">Université d'Uppsala</orgName><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName></affiliation></author><author><name sortKey="Beekly, Duane" sort="Beekly, Duane" uniqKey="Beekly D" first="Duane" last="Beekly">Duane Beekly</name><affiliation wicri:level="4"><nlm:aff id="A104">National Alzheimer’s Coordinating Center, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>National Alzheimer’s Coordinating Center, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Alvarez, Victoria" sort="Alvarez, Victoria" uniqKey="Alvarez V" first="Victoria" last="Alvarez">Victoria Alvarez</name><affiliation wicri:level="1"><nlm:aff id="A105">Genetica Molecular, Hospital Universitario Central Asturias, Oviedo, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Genetica Molecular, Hospital Universitario Central Asturias, Oviedo</wicri:regionArea><wicri:noRegion>Oviedo</wicri:noRegion></affiliation></author><author><name sortKey="Zou, Fanggeng" sort="Zou, Fanggeng" uniqKey="Zou F" first="Fanggeng" last="Zou">Fanggeng Zou</name><affiliation wicri:level="2"><nlm:aff id="A103">Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Neuroscience, Mayo Clinic, Jacksonville, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Valladares, Otto" sort="Valladares, Otto" uniqKey="Valladares O" first="Otto" last="Valladares">Otto Valladares</name><affiliation wicri:level="2"><nlm:aff id="A23">Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Younkin, Steven G" sort="Younkin, Steven G" uniqKey="Younkin S" first="Steven G" last="Younkin">Steven G. Younkin</name><affiliation wicri:level="2"><nlm:aff id="A103">Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Neuroscience, Mayo Clinic, Jacksonville, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Coto, Eliecer" sort="Coto, Eliecer" uniqKey="Coto E" first="Eliecer" last="Coto">Eliecer Coto</name><affiliation wicri:level="1"><nlm:aff id="A105">Genetica Molecular, Hospital Universitario Central Asturias, Oviedo, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Genetica Molecular, Hospital Universitario Central Asturias, Oviedo</wicri:regionArea><wicri:noRegion>Oviedo</wicri:noRegion></affiliation></author><author><name sortKey="Hamilton Nelson, Kara L" sort="Hamilton Nelson, Kara L" uniqKey="Hamilton Nelson K" first="Kara L" last="Hamilton-Nelson">Kara L. Hamilton-Nelson</name><affiliation wicri:level="2"><nlm:aff id="A13">John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Gu, Wei" sort="Gu, Wei" uniqKey="Gu W" first="Wei" last="Gu">Wei Gu</name><affiliation wicri:level="1"><nlm:aff id="A100">Department of Psychiatry, Saarland University Hospital, Homburg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Psychiatry, Saarland University Hospital, Homburg</wicri:regionArea><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion></affiliation></author><author><name sortKey="Razquin, Cristina" sort="Razquin, Cristina" uniqKey="Razquin C" first="Cristina" last="Razquin">Cristina Razquin</name><affiliation wicri:level="1"><nlm:aff id="A106">Neurogenetics Laboratory, Division of Neurosciences, Center for Applied Medical Research, University of Navarra School of Medicine, Pamplona, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Neurogenetics Laboratory, Division of Neurosciences, Center for Applied Medical Research, University of Navarra School of Medicine, Pamplona</wicri:regionArea><wicri:noRegion>Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="Pastor, Pau" sort="Pastor, Pau" uniqKey="Pastor P" first="Pau" last="Pastor">Pau Pastor</name><affiliation wicri:level="1"><nlm:aff id="A106">Neurogenetics Laboratory, Division of Neurosciences, Center for Applied Medical Research, University of Navarra School of Medicine, Pamplona, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Neurogenetics Laboratory, Division of Neurosciences, Center for Applied Medical Research, University of Navarra School of Medicine, Pamplona</wicri:regionArea><wicri:noRegion>Pamplona</wicri:noRegion></affiliation><affiliation wicri:level="3"><nlm:aff id="A107">CIBERNED, Instituto de Salud Carlos III, Madrid, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>CIBERNED, Instituto de Salud Carlos III, Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Mateo, Ignacio" sort="Mateo, Ignacio" uniqKey="Mateo I" first="Ignacio" last="Mateo">Ignacio Mateo</name><affiliation wicri:level="1"><nlm:aff id="A108">Neurology Service, Marqués de Valdecilla University Hospital, University of Cantabria and Instituto de Formación e Investigación Marqués de Valdecilla (IFIMAV), Santander, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Neurology Service, Marqués de Valdecilla University Hospital, University of Cantabria and Instituto de Formación e Investigación Marqués de Valdecilla (IFIMAV), Santander</wicri:regionArea><wicri:noRegion>Santander</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A109">CIBERNED, Marqués de Valdecilla University Hospital, University of Cantabria and IFIMAV, Santander, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>CIBERNED, Marqués de Valdecilla University Hospital, University of Cantabria and IFIMAV, Santander</wicri:regionArea><wicri:noRegion>Santander</wicri:noRegion></affiliation></author><author><name sortKey="Owen, Michael J" sort="Owen, Michael J" uniqKey="Owen M" first="Michael J" last="Owen">Michael J. Owen</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Faber, Kelley M" sort="Faber, Kelley M" uniqKey="Faber K" first="Kelley M" last="Faber">Kelley M. Faber</name><affiliation wicri:level="2"><nlm:aff id="A110">Department of Medical and Molecular Genetics, Indiana University, Indianapolis, Indiana, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medical and Molecular Genetics, Indiana University, Indianapolis, Indiana</wicri:regionArea><placeName><region type="state">Indiana</region></placeName></affiliation></author><author><name sortKey="Jonsson, Palmi V" sort="Jonsson, Palmi V" uniqKey="Jonsson P" first="Palmi V" last="Jonsson">Palmi V. Jonsson</name><affiliation wicri:level="1"><nlm:aff id="A17">Faculty of Medicine, University of Iceland, Reykjavik, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Faculty of Medicine, University of Iceland, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A111">Geriatric Department, Landspitali University Hospital, Reykjavik, Iceland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Islande</country><wicri:regionArea>Geriatric Department, Landspitali University Hospital, Reykjavik</wicri:regionArea><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Combarros, Onofre" sort="Combarros, Onofre" uniqKey="Combarros O" first="Onofre" last="Combarros">Onofre Combarros</name><affiliation wicri:level="1"><nlm:aff id="A108">Neurology Service, Marqués de Valdecilla University Hospital, University of Cantabria and Instituto de Formación e Investigación Marqués de Valdecilla (IFIMAV), Santander, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Neurology Service, Marqués de Valdecilla University Hospital, University of Cantabria and Instituto de Formación e Investigación Marqués de Valdecilla (IFIMAV), Santander</wicri:regionArea><wicri:noRegion>Santander</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A109">CIBERNED, Marqués de Valdecilla University Hospital, University of Cantabria and IFIMAV, Santander, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>CIBERNED, Marqués de Valdecilla University Hospital, University of Cantabria and IFIMAV, Santander</wicri:regionArea><wicri:noRegion>Santander</wicri:noRegion></affiliation></author><author><name sortKey="O Onovan, Michael C" sort="O Onovan, Michael C" uniqKey="O Onovan M" first="Michael C" last="O Onovan">Michael C. O Onovan</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Cantwell, Laura B" sort="Cantwell, Laura B" uniqKey="Cantwell L" first="Laura B" last="Cantwell">Laura B. Cantwell</name><affiliation wicri:level="2"><nlm:aff id="A23">Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Soininen, Hilkka" sort="Soininen, Hilkka" uniqKey="Soininen H" first="Hilkka" last="Soininen">Hilkka Soininen</name><affiliation wicri:level="1"><nlm:aff id="A112">Institute of Clinical Medicine–Neurology, University of Eastern Finland, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Institute of Clinical Medicine–Neurology, University of Eastern Finland, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A113">Department of Neurology, Kuopio University Hospital, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Neurology, Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Blacker, Deborah" sort="Blacker, Deborah" uniqKey="Blacker D" first="Deborah" last="Blacker">Deborah Blacker</name><affiliation wicri:level="2"><nlm:aff id="A114">Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A115">Department of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Mead, Simon" sort="Mead, Simon" uniqKey="Mead S" first="Simon" last="Mead">Simon Mead</name><affiliation wicri:level="3"><nlm:aff id="A74">MRC Prion Unit, Department of Neurodegenerative Disease, University College London Institute of Neurology, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>MRC Prion Unit, Department of Neurodegenerative Disease, University College London Institute of Neurology, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Mosley, Thomas H" sort="Mosley, Thomas H" uniqKey="Mosley T" first="Thomas H" last="Mosley">Thomas H. Mosley</name><affiliation wicri:level="2"><nlm:aff id="A116">Department of Medicine (Geriatrics), University of Mississippi Medical Center, Jackson, Mississippi, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine (Geriatrics), University of Mississippi Medical Center, Jackson, Mississippi</wicri:regionArea><placeName><region type="state">État du Mississippi</region></placeName></affiliation></author><author><name sortKey="Bennett, David A" sort="Bennett, David A" uniqKey="Bennett D" first="David A" last="Bennett">David A. Bennett</name><affiliation wicri:level="2"><nlm:aff id="A71">Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A117">Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B" last="Harris">Tamara B. Harris</name><affiliation wicri:level="4"><nlm:aff id="A12">Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Fratiglioni, Laura" sort="Fratiglioni, Laura" uniqKey="Fratiglioni L" first="Laura" last="Fratiglioni">Laura Fratiglioni</name><affiliation wicri:level="3"><nlm:aff id="A60">Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A118">Department of Geriatric Medicine, Karolinska University Hospital Huddinge, Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Department of Geriatric Medicine, Karolinska University Hospital Huddinge, Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Holmes, Clive" sort="Holmes, Clive" uniqKey="Holmes C" first="Clive" last="Holmes">Clive Holmes</name><affiliation wicri:level="1"><nlm:aff id="A119">Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton</wicri:regionArea><wicri:noRegion>Southampton</wicri:noRegion></affiliation></author><author><name sortKey="De Bruijn, Renee F A G" sort="De Bruijn, Renee F A G" uniqKey="De Bruijn R" first="Renee F A G" last="De Bruijn">Renee F A G. De Bruijn</name><affiliation wicri:level="3"><nlm:aff id="A4">Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Neurology, Erasmus MC University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A20">Netherlands Consortium for Healthy Aging, Leiden, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherlands Consortium for Healthy Aging, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Passmore, Peter" sort="Passmore, Peter" uniqKey="Passmore P" first="Peter" last="Passmore">Peter Passmore</name><affiliation wicri:level="1"><nlm:aff id="A43">Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen’s University, Belfast</wicri:regionArea><wicri:noRegion>Belfast</wicri:noRegion></affiliation></author><author><name sortKey="Montine, Thomas J" sort="Montine, Thomas J" uniqKey="Montine T" first="Thomas J" last="Montine">Thomas J. Montine</name><affiliation wicri:level="4"><nlm:aff id="A120">Department of Pathology, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Pathology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Bettens, Karolien" sort="Bettens, Karolien" uniqKey="Bettens K" first="Karolien" last="Bettens">Karolien Bettens</name><affiliation wicri:level="1"><nlm:aff id="A53">Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp, Belgium.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Belgique</country><wicri:regionArea>Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp</wicri:regionArea><wicri:noRegion>Antwerp</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A54">Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Belgique</country><wicri:regionArea>Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp</wicri:regionArea><orgName type="university">Université d'Anvers</orgName><placeName><settlement type="city">Anvers</settlement><region>Région flamande</region><region type="district" nuts="2">Province d'Anvers</region></placeName></affiliation></author><author><name sortKey="Rotter, Jerome I" sort="Rotter, Jerome I" uniqKey="Rotter J" first="Jerome I" last="Rotter">Jerome I. Rotter</name><affiliation wicri:level="2"><nlm:aff id="A121">Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California</wicri:regionArea><placeName><region type="state">Californie</region></placeName></affiliation></author><author><name sortKey="Brice, Alexis" sort="Brice, Alexis" uniqKey="Brice A" first="Alexis" last="Brice">Alexis Brice</name><affiliation wicri:level="4"><nlm:aff id="A122">INSERM UMRS 975, CNRS UMR 7225, Université Pierre et Marie Curie, Centre de Recherche de l’Institut du Cerveau et de la Moëlle Epinière (CRICM), Hôpital de la Salpêtrière, Paris, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM UMRS 975, CNRS UMR 7225, Université Pierre et Marie Curie, Centre de Recherche de l’Institut du Cerveau et de la Moëlle Epinière (CRICM), Hôpital de la Salpêtrière, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement><settlement type="city">Paris</settlement></placeName><orgName type="university">Université Pierre-et-Marie-Curie</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A123">Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital de la Pitié–Salpêtrière, Paris, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital de la Pitié–Salpêtrière, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Morgan, Kevin" sort="Morgan, Kevin" uniqKey="Morgan K" first="Kevin" last="Morgan">Kevin Morgan</name><affiliation wicri:level="4"><nlm:aff id="A57">Institute of Genetics, Queen’s Medical Centre, University of Nottingham, Nottingham, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Genetics, Queen’s Medical Centre, University of Nottingham, Nottingham</wicri:regionArea><orgName type="university">Université de Nottingham</orgName><placeName><settlement type="city">Nottingham</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Nottinghamshire</region></placeName></affiliation></author><author><name sortKey="Foroud, Tatiana M" sort="Foroud, Tatiana M" uniqKey="Foroud T" first="Tatiana M" last="Foroud">Tatiana M. Foroud</name><affiliation wicri:level="2"><nlm:aff id="A110">Department of Medical and Molecular Genetics, Indiana University, Indianapolis, Indiana, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medical and Molecular Genetics, Indiana University, Indianapolis, Indiana</wicri:regionArea><placeName><region type="state">Indiana</region></placeName></affiliation></author><author><name sortKey="Kukull, Walter A" sort="Kukull, Walter A" uniqKey="Kukull W" first="Walter A" last="Kukull">Walter A. Kukull</name><affiliation wicri:level="4"><nlm:aff id="A32">Department of Epidemiology, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Hannequin, Didier" sort="Hannequin, Didier" uniqKey="Hannequin D" first="Didier" last="Hannequin">Didier Hannequin</name><affiliation wicri:level="3"><nlm:aff id="A37">CNR-MAJ, INSERM, U1079, Rouen University Hospital, Rouen, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>CNR-MAJ, INSERM, U1079, Rouen University Hospital, Rouen</wicri:regionArea><placeName><region type="region">Région Normandie</region><region type="old region">Haute-Normandie</region><settlement type="city">Rouen</settlement></placeName></affiliation></author><author><name sortKey="Powell, John F" sort="Powell, John F" uniqKey="Powell J" first="John F" last="Powell">John F. Powell</name><affiliation wicri:level="3"><nlm:aff id="A49">Institute of Psychiatry, King’s College London, Denmark Hill, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychiatry, King’s College London, Denmark Hill, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Nalls, Michael A" sort="Nalls, Michael A" uniqKey="Nalls M" first="Michael A" last="Nalls">Michael A. Nalls</name><affiliation wicri:level="2"><nlm:aff id="A124">Laboratory of Neurogenetics, Intramural Research Program, National Institute on Aging, Bethesda, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Laboratory of Neurogenetics, Intramural Research Program, National Institute on Aging, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Ritchie, Karen" sort="Ritchie, Karen" uniqKey="Ritchie K" first="Karen" last="Ritchie">Karen Ritchie</name><affiliation wicri:level="3"><nlm:aff id="A44">INSERM, U1061, Faculty of Medicine, Hôpital La Colombière, Montpellier, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U1061, Faculty of Medicine, Hôpital La Colombière, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A125">Faculty of Medicine, Imperial College, St. Mary’s Hospital, London, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Faculty of Medicine, Imperial College, St. Mary’s Hospital, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Lunetta, Kathryn L" sort="Lunetta, Kathryn L" uniqKey="Lunetta K" first="Kathryn L" last="Lunetta">Kathryn L. Lunetta</name><affiliation wicri:level="2"><nlm:aff id="A11">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Kauwe, John S K" sort="Kauwe, John S K" uniqKey="Kauwe J" first="John S K" last="Kauwe">John S K. Kauwe</name><affiliation wicri:level="2"><nlm:aff id="A126">Department of Biology, Brigham Young University, Provo, Utah, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biology, Brigham Young University, Provo, Utah</wicri:regionArea><placeName><region type="state">Utah</region></placeName></affiliation></author><author><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><affiliation wicri:level="2"><nlm:aff id="A127">Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A128">Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A129">Division of Epidemiology, University of Texas Health Sciences Center at Houston, Houston, Texas, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Division of Epidemiology, University of Texas Health Sciences Center at Houston, Houston, Texas</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author><author><name sortKey="Riemenschneider, Matthias" sort="Riemenschneider, Matthias" uniqKey="Riemenschneider M" first="Matthias" last="Riemenschneider">Matthias Riemenschneider</name><affiliation wicri:level="1"><nlm:aff id="A100">Department of Psychiatry, Saarland University Hospital, Homburg, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Psychiatry, Saarland University Hospital, Homburg</wicri:regionArea><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion></affiliation></author><author><name sortKey="Boada, Merce" sort="Boada, Merce" uniqKey="Boada M" first="Mercè" last="Boada">Mercè Boada</name><affiliation wicri:level="3"><nlm:aff id="A25">Memory Clinic of Fundació Alzheimer Centre Educacional (ACE). Institut Català de Neurociències Aplicades, Barcelona, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Memory Clinic of Fundació Alzheimer Centre Educacional (ACE). Institut Català de Neurociències Aplicades, Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A130">Hospital Universitari Vall d’Hebron–Institut de Recerca, Universitat Autònoma de Barcelona. (VHIR-UAB), Barcelona, Spain.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Espagne</country><wicri:regionArea>Hospital Universitari Vall d’Hebron–Institut de Recerca, Universitat Autònoma de Barcelona. (VHIR-UAB), Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Hiltunen, Mikko" sort="Hiltunen, Mikko" uniqKey="Hiltunen M" first="Mikko" last="Hiltunen">Mikko Hiltunen</name><affiliation wicri:level="1"><nlm:aff id="A112">Institute of Clinical Medicine–Neurology, University of Eastern Finland, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Institute of Clinical Medicine–Neurology, University of Eastern Finland, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="A113">Department of Neurology, Kuopio University Hospital, Kuopio, Finland.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Finlande</country><wicri:regionArea>Department of Neurology, Kuopio University Hospital, Kuopio</wicri:regionArea><wicri:noRegion>Kuopio</wicri:noRegion></affiliation></author><author><name sortKey="Martin, Eden R" sort="Martin, Eden R" uniqKey="Martin E" first="Eden R" last="Martin">Eden R. Martin</name><affiliation wicri:level="2"><nlm:aff id="A13">John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A14">Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Schmidt, Reinhold" sort="Schmidt, Reinhold" uniqKey="Schmidt R" first="Reinhold" last="Schmidt">Reinhold Schmidt</name><affiliation wicri:level="1"><nlm:aff id="A131">Department of Neurology, Medical University of Graz, Graz, Austria.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Autriche</country><wicri:regionArea>Department of Neurology, Medical University of Graz, Graz</wicri:regionArea><wicri:noRegion>Graz</wicri:noRegion></affiliation></author><author><name sortKey="Rujescu, Dan" sort="Rujescu, Dan" uniqKey="Rujescu D" first="Dan" last="Rujescu">Dan Rujescu</name><affiliation wicri:level="1"><nlm:aff id="A132">Department of Psychiatry, University of Halle, Halle, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Department of Psychiatry, University of Halle, Halle</wicri:regionArea><wicri:noRegion>Halle</wicri:noRegion><wicri:noRegion>Halle</wicri:noRegion><wicri:noRegion>Halle</wicri:noRegion></affiliation></author><author><name sortKey="Wang, Li San" sort="Wang, Li San" uniqKey="Wang L" first="Li-San" last="Wang">Li-San Wang</name><affiliation wicri:level="2"><nlm:aff id="A23">Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Dartigues, Jean Francois" sort="Dartigues, Jean Francois" uniqKey="Dartigues J" first="Jean-François" last="Dartigues">Jean-François Dartigues</name><affiliation wicri:level="3"><nlm:aff id="A50">INSERM, U897, Victor Segalen University, Bordeaux, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U897, Victor Segalen University, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A133">Centre de Mémoire de Ressources et de Recherche de Bordeaux, Centre Hospitalier Universitaire (CHU) de Bordeaux, Bordeaux, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre de Mémoire de Ressources et de Recherche de Bordeaux, Centre Hospitalier Universitaire (CHU) de Bordeaux, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Mayeux, Richard" sort="Mayeux, Richard" uniqKey="Mayeux R" first="Richard" last="Mayeux">Richard Mayeux</name><affiliation wicri:level="4"><nlm:aff id="A26">Taub Institute on Alzheimer’s Disease and the Aging Brain, Department of Neurology, Columbia University, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Taub Institute on Alzheimer’s Disease and the Aging Brain, Department of Neurology, Columbia University, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A27">Gertrude H. Sergievsky Center, Department of Neurology, Columbia University, New York, New York, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Gertrude H. Sergievsky Center, Department of Neurology, Columbia University, New York, New York</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Tzourio, Christophe" sort="Tzourio, Christophe" uniqKey="Tzourio C" first="Christophe" last="Tzourio">Christophe Tzourio</name><affiliation wicri:level="3"><nlm:aff id="A134">INSERM, U708, Victor Segalen University, Bordeaux, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U708, Victor Segalen University, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A20">Netherlands Consortium for Healthy Aging, Leiden, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherlands Consortium for Healthy Aging, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Nothen, Markus M" sort="Nothen, Markus M" uniqKey="Nothen M" first="Markus M" last="Nöthen">Markus M. Nöthen</name><affiliation wicri:level="3"><nlm:aff id="A135">Institute of Human Genetics, Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Allemagne</country><wicri:regionArea>Institute of Human Genetics, Department of Genomics, Life and Brain Center, University of Bonn, Bonn</wicri:regionArea><placeName><region type="land" nuts="1">Rhénanie-du-Nord-Westphalie</region><region type="district" nuts="2">District de Cologne</region><settlement type="city">Bonn</settlement></placeName></affiliation></author><author><name sortKey="Graff, Caroline" sort="Graff, Caroline" uniqKey="Graff C" first="Caroline" last="Graff">Caroline Graff</name><affiliation wicri:level="2"><nlm:aff id="A117">Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A136">Department of Neurobiology, Karolinska Institutet, Care Sciences and Society, Karolinska Institute–Alzheimer’s Disease Research Center (KIADRC), Stockholm, Sweden.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Suède</country><wicri:regionArea>Department of Neurobiology, Karolinska Institutet, Care Sciences and Society, Karolinska Institute–Alzheimer’s Disease Research Center (KIADRC), Stockholm</wicri:regionArea><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M" last="Psaty">Bruce M. Psaty</name><affiliation wicri:level="4"><nlm:aff id="A12">Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="4"><nlm:aff id="A32">Department of Epidemiology, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Epidemiology, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation><affiliation wicri:level="2"><nlm:aff id="A61">Group Health Research Institute, Group Health, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Group Health Research Institute, Group Health, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A137">Department of Health Service, University of Washington, Seattle, Washington, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Health Service, University of Washington, Seattle, Washington</wicri:regionArea><placeName><region type="state">Washington (État)</region><settlement type="city">Seattle</settlement></placeName><orgName type="university">Université de Washington</orgName></affiliation></author><author><name sortKey="Jones, Lesley" sort="Jones, Lesley" uniqKey="Jones L" first="Lesley" last="Jones">Lesley Jones</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Haines, Jonathan L" sort="Haines, Jonathan L" uniqKey="Haines J" first="Jonathan L" last="Haines">Jonathan L. Haines</name><affiliation wicri:level="2"><nlm:aff id="A16">Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A138">Vanderbilt Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Vanderbilt Center for Human Genetics Research, Vanderbilt University, Nashville, Tennessee</wicri:regionArea><placeName><region type="state">Tennessee</region></placeName></affiliation></author><author><name sortKey="Holmans, Peter A" sort="Holmans, Peter A" uniqKey="Holmans P" first="Peter A" last="Holmans">Peter A. Holmans</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Lathrop, Mark" sort="Lathrop, Mark" uniqKey="Lathrop M" first="Mark" last="Lathrop">Mark Lathrop</name><affiliation wicri:level="3"><nlm:aff id="A21">Centre National de Génotypage, Institut Génomique, Commissariat à l’Energie Atomique, Evry, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre National de Génotypage, Institut Génomique, Commissariat à l’Energie Atomique, Evry</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Évry (Essonne)</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A22">Fondation Jean Dausset, Centre d’Etude du Polymorphisme Humain (CEPH), Paris, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Fondation Jean Dausset, Centre d’Etude du Polymorphisme Humain (CEPH), Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A139">McGill University and Génome Québec Innovation Centre, Montreal, Quebec, Canada.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Canada</country><wicri:regionArea>McGill University and Génome Québec Innovation Centre, Montreal, Quebec</wicri:regionArea><wicri:noRegion>Quebec</wicri:noRegion></affiliation></author><author><name sortKey="Pericak Vance, Margaret A" sort="Pericak Vance, Margaret A" uniqKey="Pericak Vance M" first="Margaret A" last="Pericak-Vance">Margaret A. Pericak-Vance</name><affiliation wicri:level="2"><nlm:aff id="A13">John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A14">Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida</wicri:regionArea><placeName><region type="state">Floride</region></placeName></affiliation></author><author><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J" last="Launer">Lenore J. Launer</name><affiliation wicri:level="2"><nlm:aff id="A140">Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, Bethesda, Maryland, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, Bethesda, Maryland</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author><author><name sortKey="Farrer, Lindsay A" sort="Farrer, Lindsay A" uniqKey="Farrer L" first="Lindsay A" last="Farrer">Lindsay A. Farrer</name><affiliation wicri:level="2"><nlm:aff id="A9">Department of Medicine (Biomedical Genetics), Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Medicine (Biomedical Genetics), Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A10">Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A11">Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A141">Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A142">Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Neurology, Boston University School of Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name><affiliation wicri:level="3"><nlm:aff id="A5">Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam</wicri:regionArea><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A20">Netherlands Consortium for Healthy Aging, Leiden, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Netherlands Consortium for Healthy Aging, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A143">Center for Medical Systems Biology, Leiden, The Netherlands.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Center for Medical Systems Biology, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Van Broeckhoven, Christine" sort="Van Broeckhoven, Christine" uniqKey="Van Broeckhoven C" first="Christine" last="Van Broeckhoven">Christine Van Broeckhoven</name><affiliation wicri:level="1"><nlm:aff id="A53">Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp, Belgium.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Belgique</country><wicri:regionArea>Neurodegenerative Brain Diseases Group, Department of Molecular Genetics, VIB, Antwerp</wicri:regionArea><wicri:noRegion>Antwerp</wicri:noRegion></affiliation><affiliation wicri:level="4"><nlm:aff id="A54">Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Belgique</country><wicri:regionArea>Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp</wicri:regionArea><orgName type="university">Université d'Anvers</orgName><placeName><settlement type="city">Anvers</settlement><region>Région flamande</region><region type="district" nuts="2">Province d'Anvers</region></placeName></affiliation></author><author><name sortKey="Moskvina, Valentina" sort="Moskvina, Valentina" uniqKey="Moskvina V" first="Valentina" last="Moskvina">Valentina Moskvina</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Seshadri, Sudha" sort="Seshadri, Sudha" uniqKey="Seshadri S" first="Sudha" last="Seshadri">Sudha Seshadri</name><affiliation wicri:level="2"><nlm:aff id="A142">Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Neurology, Boston University School of Medicine, Boston, Massachusetts</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Williams, Julie" sort="Williams, Julie" uniqKey="Williams J" first="Julie" last="Williams">Julie Williams</name><affiliation wicri:level="1"><nlm:aff id="A6">Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, UK.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>Institute of Psychological Medicine and Clinical Neurosciences, Medical Research Council (MRC) Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff</wicri:regionArea><wicri:noRegion>Cardiff</wicri:noRegion></affiliation></author><author><name sortKey="Schellenberg, Gerard D" sort="Schellenberg, Gerard D" uniqKey="Schellenberg G" first="Gerard D" last="Schellenberg">Gerard D. Schellenberg</name><affiliation wicri:level="2"><nlm:aff id="A23">Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.</nlm:aff><country xml:lang="fr" wicri:curation="lc">États-Unis</country><wicri:regionArea>Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania</wicri:regionArea><placeName><region type="state">Pennsylvanie</region></placeName></affiliation></author><author><name sortKey="Amouyel, Philippe" sort="Amouyel, Philippe" uniqKey="Amouyel P" first="Philippe" last="Amouyel">Philippe Amouyel</name><affiliation wicri:level="3"><nlm:aff id="A1">INSERM, U744, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>INSERM, U744, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation><affiliation wicri:level="4"><nlm:aff id="A2">Université Lille 2, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Université Lille 2, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement><settlement type="city">Lille</settlement></placeName><orgName type="university">Université Lille 2</orgName></affiliation><affiliation wicri:level="3"><nlm:aff id="A3">Institut Pasteur de Lille, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Institut Pasteur de Lille, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A28">Centre National de Reference pour les Malades Alzheimer Jeunes (CNR-MAJ), Centre Hospitalier Régional Universitaire de Lille, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre National de Reference pour les Malades Alzheimer Jeunes (CNR-MAJ), Centre Hospitalier Régional Universitaire de Lille, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A144">Centre Hospitalier Régional Universitaire de Lille, Lille, France.</nlm:aff><country xml:lang="fr" wicri:curation="lc">France</country><wicri:regionArea>Centre Hospitalier Régional Universitaire de Lille, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author></analytic><series><title level="j">Nature genetics</title><idno type="ISSN">1061-4036</idno><idno type="eISSN">1546-1718</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P4">Eleven susceptibility loci for late-onset Alzheimer’s disease (LOAD) were identified by previous studies; however, a large portion of the genetic risk for this disease remains unexplained. We conducted a large, two-stage meta-analysis of genome-wide association studies (GWAS) in individuals of European ancestry. In stage 1, we used genotyped and imputed data (7,055,881 SNPs) to perform meta-analysis on 4 previously published GWAS data sets consisting of 17,008 Alzheimer’s disease cases and 37,154 controls. In stage 2,11,632 SNPs were genotyped and tested for association in an independent set of 8,572 Alzheimer’s disease cases and 11,312 controls. In addition to the <italic>APOE</italic> locus (encoding apolipoprotein E), 19 loci reached genome-wide significance (<italic>P</italic> < 5 × 10<sup>−8</sup>) in the combined stage 1 and stage 2 analysis, of which 11 are newly associated with Alzheimer’s disease.</p></div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Autriche</li><li>Belgique</li><li>Canada</li><li>Espagne</li><li>Finlande</li><li>France</li><li>Grèce</li><li>Irlande (pays)</li><li>Islande</li><li>Italie</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Suisse</li><li>Suède</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Angleterre de l'Est</li><li>Aquitaine</li><li>Arizona</li><li>Bavière</li><li>Californie</li><li>Canton de Zurich</li><li>Catalogne</li><li>Communauté de Madrid</li><li>District de Cologne</li><li>District de Darmstadt</li><li>District de Haute-Bavière</li><li>East Middle Sweden</li><li>Floride</li><li>Grand Londres</li><li>Haute-Normandie</li><li>Hauts-de-France</li><li>Hesse (Land)</li><li>Hollande-Méridionale</li><li>Illinois</li><li>Indiana</li><li>Languedoc-Roussillon</li><li>Latium</li><li>Lombardie</li><li>Maryland</li><li>Massachusetts</li><li>Missouri (État)</li><li>Nord-Pas-de-Calais</li><li>Nottinghamshire</li><li>Nouvelle-Aquitaine</li><li>Occitanie (région administrative)</li><li>Ontario</li><li>Oxfordshire</li><li>Pennsylvanie</li><li>Province d'Anvers</li><li>Rhénanie-du-Nord-Westphalie</li><li>Région Normandie</li><li>Région flamande</li><li>Svealand</li><li>Tennessee</li><li>Texas</li><li>Toscane</li><li>Utah</li><li>Washington (État)</li><li>État de New York</li><li>État du Mississippi</li><li>Île-de-France</li></region><settlement><li>Anvers</li><li>Barcelone</li><li>Bonn</li><li>Bordeaux</li><li>Cambridge</li><li>Francfort-sur-le-Main</li><li>Leyde</li><li>Lille</li><li>Londres</li><li>Madrid</li><li>Milan</li><li>Montpellier</li><li>Munich</li><li>New York</li><li>Nottingham</li><li>Oxford</li><li>Paris</li><li>Pise</li><li>Pittsburgh</li><li>Rome</li><li>Rotterdam</li><li>Rouen</li><li>Saint-Louis (Missouri)</li><li>Seattle</li><li>Stockholm</li><li>Toronto</li><li>Uppsala</li><li>Zurich</li><li>Évry (Essonne)</li></settlement><orgName><li>Université Columbia</li><li>Université Lille 2</li><li>Université Louis-et-Maximilien de Munich</li><li>Université Pierre-et-Marie-Curie</li><li>Université autonome de Barcelone</li><li>Université autonome de Madrid</li><li>Université d'Anvers</li><li>Université d'Oxford</li><li>Université d'Uppsala</li><li>Université de Cambridge</li><li>Université de Nottingham</li><li>Université de Pise</li><li>Université de Pittsburgh</li><li>Université de Toronto</li><li>Université de Washington</li><li>Université de Zurich</li><li>École de médecine (Université Washington de Saint-Louis)</li></orgName></list><tree><country name="France"><region name="Hauts-de-France"><name sortKey="Lambert, Jean Charles" sort="Lambert, Jean Charles" uniqKey="Lambert J" first="Jean-Charles" last="Lambert">Jean-Charles Lambert</name></region><name sortKey="Amouyel, Philippe" sort="Amouyel, Philippe" uniqKey="Amouyel P" first="Philippe" last="Amouyel">Philippe Amouyel</name><name sortKey="Amouyel, Philippe" sort="Amouyel, Philippe" uniqKey="Amouyel P" first="Philippe" last="Amouyel">Philippe Amouyel</name><name sortKey="Amouyel, Philippe" sort="Amouyel, Philippe" uniqKey="Amouyel P" first="Philippe" last="Amouyel">Philippe Amouyel</name><name sortKey="Amouyel, Philippe" sort="Amouyel, Philippe" uniqKey="Amouyel P" first="Philippe" last="Amouyel">Philippe Amouyel</name><name sortKey="Amouyel, Philippe" sort="Amouyel, Philippe" uniqKey="Amouyel P" first="Philippe" last="Amouyel">Philippe Amouyel</name><name sortKey="Barberger Gateau, Pascale" sort="Barberger Gateau, Pascale" uniqKey="Barberger Gateau P" first="Pascale" last="Barberger-Gateau">Pascale Barberger-Gateau</name><name sortKey="Bellenguez, Celine" sort="Bellenguez, Celine" uniqKey="Bellenguez C" first="Céline" last="Bellenguez">Céline Bellenguez</name><name sortKey="Bellenguez, Celine" sort="Bellenguez, Celine" uniqKey="Bellenguez C" first="Céline" last="Bellenguez">Céline Bellenguez</name><name sortKey="Bellenguez, Celine" sort="Bellenguez, Celine" uniqKey="Bellenguez C" first="Céline" last="Bellenguez">Céline Bellenguez</name><name sortKey="Berr, Claudine" sort="Berr, Claudine" uniqKey="Berr C" first="Claudine" last="Berr">Claudine Berr</name><name sortKey="Bihoreau, Marie Therese" sort="Bihoreau, Marie Therese" uniqKey="Bihoreau M" first="Marie-Thérèse" last="Bihoreau">Marie-Thérèse Bihoreau</name><name sortKey="Brice, Alexis" sort="Brice, Alexis" uniqKey="Brice A" first="Alexis" last="Brice">Alexis Brice</name><name sortKey="Brice, Alexis" sort="Brice, Alexis" uniqKey="Brice A" first="Alexis" last="Brice">Alexis Brice</name><name sortKey="Campion, Dominique" sort="Campion, Dominique" uniqKey="Campion D" first="Dominique" last="Campion">Dominique Campion</name><name sortKey="Chouraki, Vincent" sort="Chouraki, Vincent" uniqKey="Chouraki V" first="Vincent" last="Chouraki">Vincent Chouraki</name><name sortKey="Chouraki, Vincent" sort="Chouraki, Vincent" uniqKey="Chouraki V" first="Vincent" last="Chouraki">Vincent Chouraki</name><name sortKey="Chouraki, Vincent" sort="Chouraki, Vincent" uniqKey="Chouraki V" first="Vincent" last="Chouraki">Vincent Chouraki</name><name sortKey="Dartigues, Jean Francois" sort="Dartigues, Jean Francois" uniqKey="Dartigues J" first="Jean-François" last="Dartigues">Jean-François Dartigues</name><name sortKey="Dartigues, Jean Francois" sort="Dartigues, Jean Francois" uniqKey="Dartigues J" first="Jean-François" last="Dartigues">Jean-François Dartigues</name><name sortKey="Deramecourt, Vincent" sort="Deramecourt, Vincent" uniqKey="Deramecourt V" first="Vincent" last="Deramecourt">Vincent Deramecourt</name><name sortKey="Deramecourt, Vincent" sort="Deramecourt, Vincent" uniqKey="Deramecourt V" first="Vincent" last="Deramecourt">Vincent Deramecourt</name><name sortKey="Dufouil, Carole" sort="Dufouil, Carole" uniqKey="Dufouil C" first="Carole" last="Dufouil">Carole Dufouil</name><name sortKey="Fievet, Nathalie" sort="Fievet, Nathalie" uniqKey="Fievet N" first="Nathalie" last="Fiévet">Nathalie Fiévet</name><name sortKey="Fievet, Nathalie" sort="Fievet, Nathalie" uniqKey="Fievet N" first="Nathalie" last="Fiévet">Nathalie Fiévet</name><name sortKey="Grenier Boley, Benjamin" sort="Grenier Boley, Benjamin" uniqKey="Grenier Boley B" first="Benjamin" last="Grenier-Boley">Benjamin Grenier-Boley</name><name sortKey="Grenier Boley, Benjamin" sort="Grenier Boley, Benjamin" uniqKey="Grenier Boley B" first="Benjamin" last="Grenier-Boley">Benjamin Grenier-Boley</name><name sortKey="Grenier Boley, Benjamin" sort="Grenier Boley, Benjamin" uniqKey="Grenier Boley B" first="Benjamin" last="Grenier-Boley">Benjamin Grenier-Boley</name><name sortKey="Hannequin, Didier" sort="Hannequin, Didier" uniqKey="Hannequin D" first="Didier" last="Hannequin">Didier Hannequin</name><name sortKey="Hanon, Olivier" sort="Hanon, Olivier" uniqKey="Hanon O" first="Olivier" last="Hanon">Olivier Hanon</name><name sortKey="Kamatani, Yoichiro" sort="Kamatani, Yoichiro" uniqKey="Kamatani Y" first="Yoichiro" last="Kamatani">Yoichiro Kamatani</name><name sortKey="Lambert, Jean Charles" sort="Lambert, Jean Charles" uniqKey="Lambert J" first="Jean-Charles" last="Lambert">Jean-Charles Lambert</name><name sortKey="Lambert, Jean Charles" sort="Lambert, Jean Charles" uniqKey="Lambert J" first="Jean-Charles" last="Lambert">Jean-Charles Lambert</name><name sortKey="Lathrop, Mark" sort="Lathrop, Mark" uniqKey="Lathrop M" first="Mark" last="Lathrop">Mark Lathrop</name><name sortKey="Lathrop, Mark" sort="Lathrop, Mark" uniqKey="Lathrop M" first="Mark" last="Lathrop">Mark Lathrop</name><name sortKey="Letenneur, Luc" sort="Letenneur, Luc" uniqKey="Letenneur L" first="Luc" last="Letenneur">Luc Letenneur</name><name sortKey="Pasquier, Florence" sort="Pasquier, Florence" uniqKey="Pasquier F" first="Florence" last="Pasquier">Florence Pasquier</name><name sortKey="Pasquier, Florence" sort="Pasquier, Florence" uniqKey="Pasquier F" first="Florence" last="Pasquier">Florence Pasquier</name><name sortKey="Ritchie, Karen" sort="Ritchie, Karen" uniqKey="Ritchie K" first="Karen" last="Ritchie">Karen Ritchie</name><name sortKey="Tzourio, Christophe" sort="Tzourio, Christophe" uniqKey="Tzourio C" first="Christophe" last="Tzourio">Christophe Tzourio</name><name sortKey="Wallon, David" sort="Wallon, David" uniqKey="Wallon D" first="David" last="Wallon">David Wallon</name><name sortKey="Zelenika, Diana" sort="Zelenika, Diana" uniqKey="Zelenika D" first="Diana" last="Zelenika">Diana Zelenika</name></country><country name="Pays-Bas"><region name="Hollande-Méridionale"><name sortKey="Ibrahim Verbaas, Carla A" sort="Ibrahim Verbaas, Carla A" uniqKey="Ibrahim Verbaas C" first="Carla A" last="Ibrahim-Verbaas">Carla A. Ibrahim-Verbaas</name></region><name sortKey="Amin, Najaf" sort="Amin, Najaf" uniqKey="Amin N" first="Najaf" last="Amin">Najaf Amin</name><name sortKey="De Bruijn, Renee F A G" sort="De Bruijn, Renee F A G" uniqKey="De Bruijn R" first="Renee F A G" last="De Bruijn">Renee F A G. De Bruijn</name><name sortKey="De Bruijn, Renee F A G" sort="De Bruijn, Renee F A G" uniqKey="De Bruijn R" first="Renee F A G" last="De Bruijn">Renee F A G. De Bruijn</name><name sortKey="De Bruijn, Renee F A G" sort="De Bruijn, Renee F A G" uniqKey="De Bruijn R" first="Renee F A G" last="De Bruijn">Renee F A G. De Bruijn</name><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><name sortKey="Hofman, Albert" sort="Hofman, Albert" uniqKey="Hofman A" first="Albert" last="Hofman">Albert Hofman</name><name sortKey="Ibrahim Verbaas, Carla A" sort="Ibrahim Verbaas, Carla A" uniqKey="Ibrahim Verbaas C" first="Carla A" last="Ibrahim-Verbaas">Carla A. Ibrahim-Verbaas</name><name sortKey="Ikram, M Arfan" sort="Ikram, M Arfan" uniqKey="Ikram M" first="M Arfan" last="Ikram">M Arfan Ikram</name><name sortKey="Ikram, M Arfan" sort="Ikram, M Arfan" uniqKey="Ikram M" first="M Arfan" last="Ikram">M Arfan Ikram</name><name sortKey="Ikram, M Arfan" sort="Ikram, M Arfan" uniqKey="Ikram M" first="M Arfan" last="Ikram">M Arfan Ikram</name><name sortKey="Ikram, M Arfan" sort="Ikram, M Arfan" uniqKey="Ikram M" first="M Arfan" last="Ikram">M Arfan Ikram</name><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name><name sortKey="Van Duijn, Cornelia M" sort="Van Duijn, Cornelia M" uniqKey="Van Duijn C" first="Cornelia M" last="Van Duijn">Cornelia M. Van Duijn</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Harold, Denise" sort="Harold, Denise" uniqKey="Harold D" first="Denise" last="Harold">Denise Harold</name></noRegion><name sortKey="Bayer, Anthony" sort="Bayer, Anthony" uniqKey="Bayer A" first="Anthony" last="Bayer">Anthony Bayer</name><name sortKey="Brayne, Carol" sort="Brayne, Carol" uniqKey="Brayne C" first="Carol" last="Brayne">Carol Brayne</name><name sortKey="Brown, Kristelle" sort="Brown, Kristelle" uniqKey="Brown K" first="Kristelle" last="Brown">Kristelle Brown</name><name sortKey="Clarke, Robert" sort="Clarke, Robert" uniqKey="Clarke R" first="Robert" last="Clarke">Robert Clarke</name><name sortKey="Collinge, John" sort="Collinge, John" uniqKey="Collinge J" first="John" last="Collinge">John Collinge</name><name sortKey="Craig, David" sort="Craig, David" uniqKey="Craig D" first="David" last="Craig">David Craig</name><name sortKey="Dunstan, Melanie L" sort="Dunstan, Melanie L" uniqKey="Dunstan M" first="Melanie L" last="Dunstan">Melanie L. Dunstan</name><name sortKey="Fox, Nick C" sort="Fox, Nick C" uniqKey="Fox N" first="Nick C" last="Fox">Nick C. Fox</name><name sortKey="Gallacher, John" sort="Gallacher, John" uniqKey="Gallacher J" first="John" last="Gallacher">John Gallacher</name><name sortKey="Gerrish, Amy" sort="Gerrish, Amy" uniqKey="Gerrish A" first="Amy" last="Gerrish">Amy Gerrish</name><name sortKey="Hardy, John" sort="Hardy, John" uniqKey="Hardy J" first="John" last="Hardy">John Hardy</name><name sortKey="Hardy, John" sort="Hardy, John" uniqKey="Hardy J" first="John" last="Hardy">John Hardy</name><name sortKey="Hollingworth, Paul" sort="Hollingworth, Paul" uniqKey="Hollingworth P" first="Paul" last="Hollingworth">Paul Hollingworth</name><name sortKey="Holmans, Peter A" sort="Holmans, Peter A" uniqKey="Holmans P" first="Peter A" last="Holmans">Peter A. Holmans</name><name sortKey="Holmes, Clive" sort="Holmes, Clive" uniqKey="Holmes C" first="Clive" last="Holmes">Clive Holmes</name><name sortKey="Johnston, Janet A" sort="Johnston, Janet A" uniqKey="Johnston J" first="Janet A" last="Johnston">Janet A. Johnston</name><name sortKey="Jones, Lesley" sort="Jones, Lesley" uniqKey="Jones L" first="Lesley" last="Jones">Lesley Jones</name><name sortKey="Jones, Nicola" sort="Jones, Nicola" uniqKey="Jones N" first="Nicola" last="Jones">Nicola Jones</name><name sortKey="Love, Seth" sort="Love, Seth" uniqKey="Love S" first="Seth" last="Love">Seth Love</name><name sortKey="Lovestone, Simon" sort="Lovestone, Simon" uniqKey="Lovestone S" first="Simon" last="Lovestone">Simon Lovestone</name><name sortKey="Matthews, Fiona" sort="Matthews, Fiona" uniqKey="Matthews F" first="Fiona" last="Matthews">Fiona Matthews</name><name sortKey="Mcguinness, Bernadette" sort="Mcguinness, Bernadette" uniqKey="Mcguinness B" first="Bernadette" last="Mcguinness">Bernadette Mcguinness</name><name sortKey="Mead, Simon" sort="Mead, Simon" uniqKey="Mead S" first="Simon" last="Mead">Simon Mead</name><name sortKey="Morgan, Kevin" sort="Morgan, Kevin" uniqKey="Morgan K" first="Kevin" last="Morgan">Kevin Morgan</name><name sortKey="Moskvina, Valentina" sort="Moskvina, Valentina" uniqKey="Moskvina V" first="Valentina" last="Moskvina">Valentina Moskvina</name><name sortKey="O Onovan, Michael C" sort="O Onovan, Michael C" uniqKey="O Onovan M" first="Michael C" last="O Onovan">Michael C. O Onovan</name><name sortKey="Owen, Michael J" sort="Owen, Michael J" uniqKey="Owen M" first="Michael J" last="Owen">Michael J. Owen</name><name sortKey="Passmore, Peter" sort="Passmore, Peter" uniqKey="Passmore P" first="Peter" last="Passmore">Peter Passmore</name><name sortKey="Powell, John F" sort="Powell, John F" uniqKey="Powell J" first="John F" last="Powell">John F. Powell</name><name sortKey="Proitsi, Petroula" sort="Proitsi, Petroula" uniqKey="Proitsi P" first="Petroula" last="Proitsi">Petroula Proitsi</name><name sortKey="Ritchie, Karen" sort="Ritchie, Karen" uniqKey="Ritchie K" first="Karen" last="Ritchie">Karen Ritchie</name><name sortKey="Rubinsztein, David C" sort="Rubinsztein, David C" uniqKey="Rubinsztein D" first="David C" last="Rubinsztein">David C. Rubinsztein</name><name sortKey="Sims, Rebecca" sort="Sims, Rebecca" uniqKey="Sims R" first="Rebecca" last="Sims">Rebecca Sims</name><name sortKey="St George Hyslop, Peter" sort="St George Hyslop, Peter" uniqKey="St George Hyslop P" first="Peter" last="St George-Hyslop">Peter St George-Hyslop</name><name sortKey="St George Hyslop, Peter" sort="St George Hyslop, Peter" uniqKey="St George Hyslop P" first="Peter" last="St George-Hyslop">Peter St George-Hyslop</name><name sortKey="Thomas, Charlene" sort="Thomas, Charlene" uniqKey="Thomas C" first="Charlene" last="Thomas">Charlene Thomas</name><name sortKey="Todd, Stephen" sort="Todd, Stephen" uniqKey="Todd S" first="Stephen" last="Todd">Stephen Todd</name><name sortKey="Williams, Julie" sort="Williams, Julie" uniqKey="Williams J" first="Julie" last="Williams">Julie Williams</name></country><country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Naj, Adam C" sort="Naj, Adam C" uniqKey="Naj A" first="Adam C" last="Naj">Adam C. Naj</name></region><name sortKey="Baldwin, Clinton" sort="Baldwin, Clinton" uniqKey="Baldwin C" first="Clinton" last="Baldwin">Clinton Baldwin</name><name sortKey="Beecham, Gary W" sort="Beecham, Gary W" uniqKey="Beecham G" first="Gary W" last="Beecham">Gary W. Beecham</name><name sortKey="Beecham, Gary W" sort="Beecham, Gary W" uniqKey="Beecham G" first="Gary W" last="Beecham">Gary W. Beecham</name><name sortKey="Beekly, Duane" sort="Beekly, Duane" uniqKey="Beekly D" first="Duane" last="Beekly">Duane Beekly</name><name sortKey="Bennett, David A" sort="Bennett, David A" uniqKey="Bennett D" first="David A" last="Bennett">David A. Bennett</name><name sortKey="Bennett, David A" sort="Bennett, David A" uniqKey="Bennett D" first="David A" last="Bennett">David A. Bennett</name><name sortKey="Bis, Joshua C" sort="Bis, Joshua C" uniqKey="Bis J" first="Joshua C" last="Bis">Joshua C. Bis</name><name sortKey="Blacker, Deborah" sort="Blacker, Deborah" uniqKey="Blacker D" first="Deborah" last="Blacker">Deborah Blacker</name><name sortKey="Blacker, Deborah" sort="Blacker, Deborah" uniqKey="Blacker D" first="Deborah" last="Blacker">Deborah Blacker</name><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><name sortKey="Boerwinkle, Eric" sort="Boerwinkle, Eric" uniqKey="Boerwinkle E" first="Eric" last="Boerwinkle">Eric Boerwinkle</name><name sortKey="Buxbaum, Joseph D" sort="Buxbaum, Joseph D" uniqKey="Buxbaum J" first="Joseph D" last="Buxbaum">Joseph D. Buxbaum</name><name sortKey="Buxbaum, Joseph D" sort="Buxbaum, Joseph D" uniqKey="Buxbaum J" first="Joseph D" last="Buxbaum">Joseph D. Buxbaum</name><name sortKey="Buxbaum, Joseph D" sort="Buxbaum, Joseph D" uniqKey="Buxbaum J" first="Joseph D" last="Buxbaum">Joseph D. Buxbaum</name><name sortKey="Cantwell, Laura B" sort="Cantwell, Laura B" uniqKey="Cantwell L" first="Laura B" last="Cantwell">Laura B. Cantwell</name><name sortKey="Carrasquillo, Minerva M" sort="Carrasquillo, Minerva M" uniqKey="Carrasquillo M" first="Minerva M" last="Carrasquillo">Minerva M. Carrasquillo</name><name sortKey="Choi, Seung Hoan" sort="Choi, Seung Hoan" uniqKey="Choi S" first="Seung-Hoan" last="Choi">Seung-Hoan Choi</name><name sortKey="Crane, Paul K" sort="Crane, Paul K" uniqKey="Crane P" first="Paul K" last="Crane">Paul K. Crane</name><name sortKey="Cruchaga, Carlos" sort="Cruchaga, Carlos" uniqKey="Cruchaga C" first="Carlos" last="Cruchaga">Carlos Cruchaga</name><name sortKey="Cruchaga, Carlos" sort="Cruchaga, Carlos" uniqKey="Cruchaga C" first="Carlos" last="Cruchaga">Carlos Cruchaga</name><name sortKey="De Jager, Philip L" sort="De Jager, Philip L" uniqKey="De Jager P" first="Philip L" last="De Jager">Philip L. De Jager</name><name sortKey="De Jager, Philip L" sort="De Jager, Philip L" uniqKey="De Jager P" first="Philip L" last="De Jager">Philip L. De Jager</name><name sortKey="Destefano, Anita L" sort="Destefano, Anita L" uniqKey="Destefano A" first="Anita L" last="Destefano">Anita L. Destefano</name><name sortKey="Evans, Denis" sort="Evans, Denis" uniqKey="Evans D" first="Denis" last="Evans">Denis Evans</name><name sortKey="Faber, Kelley M" sort="Faber, Kelley M" uniqKey="Faber K" first="Kelley M" last="Faber">Kelley M. Faber</name><name sortKey="Farrer, Lindsay A" sort="Farrer, Lindsay A" uniqKey="Farrer L" first="Lindsay A" last="Farrer">Lindsay A. Farrer</name><name sortKey="Farrer, Lindsay A" sort="Farrer, Lindsay A" uniqKey="Farrer L" first="Lindsay A" last="Farrer">Lindsay A. Farrer</name><name sortKey="Farrer, Lindsay A" sort="Farrer, Lindsay A" uniqKey="Farrer L" first="Lindsay A" last="Farrer">Lindsay A. Farrer</name><name sortKey="Farrer, Lindsay A" sort="Farrer, Lindsay A" uniqKey="Farrer L" first="Lindsay A" last="Farrer">Lindsay A. Farrer</name><name sortKey="Farrer, Lindsay A" sort="Farrer, Lindsay A" uniqKey="Farrer L" first="Lindsay A" last="Farrer">Lindsay A. Farrer</name><name sortKey="Fitzpatrick, Annette L" sort="Fitzpatrick, Annette L" uniqKey="Fitzpatrick A" first="Annette L" last="Fitzpatrick">Annette L. Fitzpatrick</name><name sortKey="Fitzpatrick, Annette L" sort="Fitzpatrick, Annette L" uniqKey="Fitzpatrick A" first="Annette L" last="Fitzpatrick">Annette L. Fitzpatrick</name><name sortKey="Fitzpatrick, Annette L" sort="Fitzpatrick, Annette L" uniqKey="Fitzpatrick A" first="Annette L" last="Fitzpatrick">Annette L. Fitzpatrick</name><name sortKey="Foroud, Tatiana M" sort="Foroud, Tatiana M" uniqKey="Foroud T" first="Tatiana M" last="Foroud">Tatiana M. Foroud</name><name sortKey="Gilbert, John R" sort="Gilbert, John R" uniqKey="Gilbert J" first="John R" last="Gilbert">John R. Gilbert</name><name sortKey="Gilbert, John R" sort="Gilbert, John R" uniqKey="Gilbert J" first="John R" last="Gilbert">John R. Gilbert</name><name sortKey="Goate, Alison M" sort="Goate, Alison M" uniqKey="Goate A" first="Alison M" last="Goate">Alison M. Goate</name><name sortKey="Goate, Alison M" sort="Goate, Alison M" uniqKey="Goate A" first="Alison M" last="Goate">Alison M. Goate</name><name sortKey="Graff, Caroline" sort="Graff, Caroline" uniqKey="Graff C" first="Caroline" last="Graff">Caroline Graff</name><name sortKey="Green, Robert" sort="Green, Robert" uniqKey="Green R" first="Robert" last="Green">Robert Green</name><name sortKey="Haines, Jonathan L" sort="Haines, Jonathan L" uniqKey="Haines J" first="Jonathan L" last="Haines">Jonathan L. Haines</name><name sortKey="Haines, Jonathan L" sort="Haines, Jonathan L" uniqKey="Haines J" first="Jonathan L" last="Haines">Jonathan L. Haines</name><name sortKey="Hakonarson, Hakon" sort="Hakonarson, Hakon" uniqKey="Hakonarson H" first="Hakon" last="Hakonarson">Hakon Hakonarson</name><name sortKey="Hamilton Nelson, Kara L" sort="Hamilton Nelson, Kara L" uniqKey="Hamilton Nelson K" first="Kara L" last="Hamilton-Nelson">Kara L. Hamilton-Nelson</name><name sortKey="Harris, Tamara B" sort="Harris, Tamara B" uniqKey="Harris T" first="Tamara B" last="Harris">Tamara B. Harris</name><name sortKey="Huentelman, Matthew J" sort="Huentelman, Matthew J" uniqKey="Huentelman M" first="Matthew J" last="Huentelman">Matthew J. Huentelman</name><name sortKey="Jun, Gyungah" sort="Jun, Gyungah" uniqKey="Jun G" first="Gyungah" last="Jun">Gyungah Jun</name><name sortKey="Jun, Gyungah" sort="Jun, Gyungah" uniqKey="Jun G" first="Gyungah" last="Jun">Gyungah Jun</name><name sortKey="Jun, Gyungah" sort="Jun, Gyungah" uniqKey="Jun G" first="Gyungah" last="Jun">Gyungah Jun</name><name sortKey="Kamboh, M Ilyas" sort="Kamboh, M Ilyas" uniqKey="Kamboh M" first="M Ilyas" last="Kamboh">M Ilyas Kamboh</name><name sortKey="Kamboh, M Ilyas" sort="Kamboh, M Ilyas" uniqKey="Kamboh M" first="M Ilyas" last="Kamboh">M Ilyas Kamboh</name><name sortKey="Kauwe, John S K" sort="Kauwe, John S K" uniqKey="Kauwe J" first="John S K" last="Kauwe">John S K. Kauwe</name><name sortKey="Kukull, Walter A" sort="Kukull, Walter A" uniqKey="Kukull W" first="Walter A" last="Kukull">Walter A. Kukull</name><name sortKey="Kunkle, Brian" sort="Kunkle, Brian" uniqKey="Kunkle B" first="Brian" last="Kunkle">Brian Kunkle</name><name sortKey="Larson, Eric B" sort="Larson, Eric B" uniqKey="Larson E" first="Eric B" last="Larson">Eric B. Larson</name><name sortKey="Larson, Eric B" sort="Larson, Eric B" uniqKey="Larson E" first="Eric B" last="Larson">Eric B. Larson</name><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J" last="Launer">Lenore J. Launer</name><name sortKey="Lin, Chiao Feng" sort="Lin, Chiao Feng" uniqKey="Lin C" first="Chiao-Feng" last="Lin">Chiao-Feng Lin</name><name sortKey="Lopez, Oscar L" sort="Lopez, Oscar L" uniqKey="Lopez O" first="Oscar L" last="Lopez">Oscar L. Lopez</name><name sortKey="Lunetta, Kathryn L" sort="Lunetta, Kathryn L" uniqKey="Lunetta K" first="Kathryn L" last="Lunetta">Kathryn L. Lunetta</name><name sortKey="Martin, Eden R" sort="Martin, Eden R" uniqKey="Martin E" first="Eden R" last="Martin">Eden R. Martin</name><name sortKey="Martin, Eden R" sort="Martin, Eden R" uniqKey="Martin E" first="Eden R" last="Martin">Eden R. Martin</name><name sortKey="Mayeux, Richard" sort="Mayeux, Richard" uniqKey="Mayeux R" first="Richard" last="Mayeux">Richard Mayeux</name><name sortKey="Mayeux, Richard" sort="Mayeux, Richard" uniqKey="Mayeux R" first="Richard" last="Mayeux">Richard Mayeux</name><name sortKey="Montine, Thomas J" sort="Montine, Thomas J" uniqKey="Montine T" first="Thomas J" last="Montine">Thomas J. Montine</name><name sortKey="Mosley, Thomas H" sort="Mosley, Thomas H" uniqKey="Mosley T" first="Thomas H" last="Mosley">Thomas H. Mosley</name><name sortKey="Myers, Amanda J" sort="Myers, Amanda J" uniqKey="Myers A" first="Amanda J" last="Myers">Amanda J. Myers</name><name sortKey="Naj, Adam C" sort="Naj, Adam C" uniqKey="Naj A" first="Adam C" last="Naj">Adam C. Naj</name><name sortKey="Nalls, Michael A" sort="Nalls, Michael A" uniqKey="Nalls M" first="Michael A" last="Nalls">Michael A. Nalls</name><name sortKey="Pericak Vance, Margaret A" sort="Pericak Vance, Margaret A" uniqKey="Pericak Vance M" first="Margaret A" last="Pericak-Vance">Margaret A. Pericak-Vance</name><name sortKey="Pericak Vance, Margaret A" sort="Pericak Vance, Margaret A" uniqKey="Pericak Vance M" first="Margaret A" last="Pericak-Vance">Margaret A. Pericak-Vance</name><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M" last="Psaty">Bruce M. Psaty</name><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M" last="Psaty">Bruce M. Psaty</name><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M" last="Psaty">Bruce M. Psaty</name><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M" last="Psaty">Bruce M. Psaty</name><name sortKey="Reitz, Christiane" sort="Reitz, Christiane" uniqKey="Reitz C" first="Christiane" last="Reitz">Christiane Reitz</name><name sortKey="Reitz, Christiane" sort="Reitz, Christiane" uniqKey="Reitz C" first="Christiane" last="Reitz">Christiane Reitz</name><name sortKey="Rotter, Jerome I" sort="Rotter, Jerome I" uniqKey="Rotter J" first="Jerome I" last="Rotter">Jerome I. Rotter</name><name sortKey="Schellenberg, Gerard D" sort="Schellenberg, Gerard D" uniqKey="Schellenberg G" first="Gerard D" last="Schellenberg">Gerard D. Schellenberg</name><name sortKey="Seshadri, Sudha" sort="Seshadri, Sudha" uniqKey="Seshadri S" first="Sudha" last="Seshadri">Sudha Seshadri</name><name sortKey="Thornton Wells, Tricia A" sort="Thornton Wells, Tricia A" uniqKey="Thornton Wells T" first="Tricia A" last="Thornton-Wells">Tricia A. Thornton-Wells</name><name sortKey="Tsuang, Debby W" sort="Tsuang, Debby W" uniqKey="Tsuang D" first="Debby W" last="Tsuang">Debby W. Tsuang</name><name sortKey="Valladares, Otto" sort="Valladares, Otto" uniqKey="Valladares O" first="Otto" last="Valladares">Otto Valladares</name><name sortKey="Vardarajan, Badri N" sort="Vardarajan, Badri N" uniqKey="Vardarajan B" first="Badri N" last="Vardarajan">Badri N. Vardarajan</name><name sortKey="Wang, Li San" sort="Wang, Li San" uniqKey="Wang L" first="Li-San" last="Wang">Li-San Wang</name><name sortKey="Younkin, Steven G" sort="Younkin, Steven G" uniqKey="Younkin S" first="Steven G" last="Younkin">Steven G. Younkin</name><name sortKey="Yu, Lei" sort="Yu, Lei" uniqKey="Yu L" first="Lei" last="Yu">Lei Yu</name><name sortKey="Zou, Fanggeng" sort="Zou, Fanggeng" uniqKey="Zou F" first="Fanggeng" last="Zou">Fanggeng Zou</name></country><country name="Suisse"><region name="Canton de Zurich"><name sortKey="Russo, Giancarlo" sort="Russo, Giancarlo" uniqKey="Russo G" first="Giancarlo" last="Russo">Giancarlo Russo</name></region></country><country name="Islande"><noRegion><name sortKey="Smith, Albert V" sort="Smith, Albert V" uniqKey="Smith A" first="Albert V" last="Smith">Albert V. Smith</name></noRegion><name sortKey="Eiriksdottir, Gudny" sort="Eiriksdottir, Gudny" uniqKey="Eiriksdottir G" first="Gudny" last="Eiriksdottir">Gudny Eiriksdottir</name><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><name sortKey="Jonsson, Palmi V" sort="Jonsson, Palmi V" uniqKey="Jonsson P" first="Palmi V" last="Jonsson">Palmi V. Jonsson</name><name sortKey="Jonsson, Palmi V" sort="Jonsson, Palmi V" uniqKey="Jonsson P" first="Palmi V" last="Jonsson">Palmi V. Jonsson</name><name sortKey="Smith, Albert V" sort="Smith, Albert V" uniqKey="Smith A" first="Albert V" last="Smith">Albert V. Smith</name></country><country name="Autriche"><noRegion><name sortKey="Schmidt, Helena" sort="Schmidt, Helena" uniqKey="Schmidt H" first="Helena" last="Schmidt">Helena Schmidt</name></noRegion><name sortKey="Schmidt, Reinhold" sort="Schmidt, Reinhold" uniqKey="Schmidt R" first="Reinhold" last="Schmidt">Reinhold Schmidt</name></country><country name="Espagne"><region name="Catalogne"><name sortKey="Ruiz, Agustin" sort="Ruiz, Agustin" uniqKey="Ruiz A" first="Agustin" last="Ruiz">Agustin Ruiz</name></region><name sortKey="Alvarez, Victoria" sort="Alvarez, Victoria" uniqKey="Alvarez V" first="Victoria" last="Alvarez">Victoria Alvarez</name><name sortKey="Boada, Merce" sort="Boada, Merce" uniqKey="Boada M" first="Mercè" last="Boada">Mercè Boada</name><name sortKey="Boada, Merce" sort="Boada, Merce" uniqKey="Boada M" first="Mercè" last="Boada">Mercè Boada</name><name sortKey="Bullido, Maria" sort="Bullido, Maria" uniqKey="Bullido M" first="Maria" last="Bullido">Maria Bullido</name><name sortKey="Bullido, Maria" sort="Bullido, Maria" uniqKey="Bullido M" first="Maria" last="Bullido">Maria Bullido</name><name sortKey="Bullido, Maria" sort="Bullido, Maria" uniqKey="Bullido M" first="Maria" last="Bullido">Maria Bullido</name><name sortKey="Clarimon, Jordi" sort="Clarimon, Jordi" uniqKey="Clarimon J" first="Jordi" last="Clarimon">Jordi Clarimon</name><name sortKey="Clarimon, Jordi" sort="Clarimon, Jordi" uniqKey="Clarimon J" first="Jordi" last="Clarimon">Jordi Clarimon</name><name sortKey="Combarros, Onofre" sort="Combarros, Onofre" uniqKey="Combarros O" first="Onofre" last="Combarros">Onofre Combarros</name><name sortKey="Combarros, Onofre" sort="Combarros, Onofre" uniqKey="Combarros O" first="Onofre" last="Combarros">Onofre Combarros</name><name sortKey="Coto, Eliecer" sort="Coto, Eliecer" uniqKey="Coto E" first="Eliecer" last="Coto">Eliecer Coto</name><name sortKey="Deniz Naranjo, Maria Candida" sort="Deniz Naranjo, Maria Candida" uniqKey="Deniz Naranjo M" first="Maria Candida" last="Deniz Naranjo">Maria Candida Deniz Naranjo</name><name sortKey="Lleo, Alberto" sort="Lleo, Alberto" uniqKey="Lleo A" first="Alberto" last="Lleo">Alberto Lleo</name><name sortKey="Lleo, Alberto" sort="Lleo, Alberto" uniqKey="Lleo A" first="Alberto" last="Lleo">Alberto Lleo</name><name sortKey="Mateo, Ignacio" sort="Mateo, Ignacio" uniqKey="Mateo I" first="Ignacio" last="Mateo">Ignacio Mateo</name><name sortKey="Mateo, Ignacio" sort="Mateo, Ignacio" uniqKey="Mateo I" first="Ignacio" last="Mateo">Ignacio Mateo</name><name sortKey="Mor N, Francisco J" sort="Mor N, Francisco J" uniqKey="Mor N F" first="Francisco J" last="Mor N">Francisco J. Mor N</name><name sortKey="Pastor, Pau" sort="Pastor, Pau" uniqKey="Pastor P" first="Pau" last="Pastor">Pau Pastor</name><name sortKey="Pastor, Pau" sort="Pastor, Pau" uniqKey="Pastor P" first="Pau" last="Pastor">Pau Pastor</name><name sortKey="Razquin, Cristina" sort="Razquin, Cristina" uniqKey="Razquin C" first="Cristina" last="Razquin">Cristina Razquin</name><name sortKey="Sanchez Garcia, Florentino" sort="Sanchez Garcia, Florentino" uniqKey="Sanchez Garcia F" first="Florentino" last="Sanchez-Garcia">Florentino Sanchez-Garcia</name></country><country name="Allemagne"><region name="Rhénanie-du-Nord-Westphalie"><name sortKey="Ramirez, Alfredo" sort="Ramirez, Alfredo" uniqKey="Ramirez A" first="Alfredo" last="Ramirez">Alfredo Ramirez</name></region><name sortKey="Becker, Tim" sort="Becker, Tim" uniqKey="Becker T" first="Tim" last="Becker">Tim Becker</name><name sortKey="Becker, Tim" sort="Becker, Tim" uniqKey="Becker T" first="Tim" last="Becker">Tim Becker</name><name sortKey="Gu, Wei" sort="Gu, Wei" uniqKey="Gu W" first="Wei" last="Gu">Wei Gu</name><name sortKey="Hampel, Harald" sort="Hampel, Harald" uniqKey="Hampel H" first="Harald" last="Hampel">Harald Hampel</name><name sortKey="Hampel, Harald" sort="Hampel, Harald" uniqKey="Hampel H" first="Harald" last="Hampel">Harald Hampel</name><name sortKey="Maier, Wolfgang" sort="Maier, Wolfgang" uniqKey="Maier W" first="Wolfgang" last="Maier">Wolfgang Maier</name><name sortKey="Maier, Wolfgang" sort="Maier, Wolfgang" uniqKey="Maier W" first="Wolfgang" last="Maier">Wolfgang Maier</name><name sortKey="Mayhaus, Manuel" sort="Mayhaus, Manuel" uniqKey="Mayhaus M" first="Manuel" last="Mayhaus">Manuel Mayhaus</name><name sortKey="Moebus, Susanne" sort="Moebus, Susanne" uniqKey="Moebus S" first="Susanne" last="Moebus">Susanne Moebus</name><name sortKey="Nothen, Markus M" sort="Nothen, Markus M" uniqKey="Nothen M" first="Markus M" last="Nöthen">Markus M. Nöthen</name><name sortKey="Pichler, Sabrina" sort="Pichler, Sabrina" uniqKey="Pichler S" first="Sabrina" last="Pichler">Sabrina Pichler</name><name sortKey="Ramirez, Alfredo" sort="Ramirez, Alfredo" uniqKey="Ramirez A" first="Alfredo" last="Ramirez">Alfredo Ramirez</name><name sortKey="Riemenschneider, Matthias" sort="Riemenschneider, Matthias" uniqKey="Riemenschneider M" first="Matthias" last="Riemenschneider">Matthias Riemenschneider</name><name sortKey="Rujescu, Dan" sort="Rujescu, Dan" uniqKey="Rujescu D" first="Dan" last="Rujescu">Dan Rujescu</name></country><country name="Belgique"><noRegion><name sortKey="Sleegers, Kristel" sort="Sleegers, Kristel" uniqKey="Sleegers K" first="Kristel" last="Sleegers">Kristel Sleegers</name></noRegion><name sortKey="Bettens, Karolien" sort="Bettens, Karolien" uniqKey="Bettens K" first="Karolien" last="Bettens">Karolien Bettens</name><name sortKey="Bettens, Karolien" sort="Bettens, Karolien" uniqKey="Bettens K" first="Karolien" last="Bettens">Karolien Bettens</name><name sortKey="Sleegers, Kristel" sort="Sleegers, Kristel" uniqKey="Sleegers K" first="Kristel" last="Sleegers">Kristel Sleegers</name><name sortKey="Van Broeckhoven, Christine" sort="Van Broeckhoven, Christine" uniqKey="Van Broeckhoven C" first="Christine" last="Van Broeckhoven">Christine Van Broeckhoven</name><name sortKey="Van Broeckhoven, Christine" sort="Van Broeckhoven, Christine" uniqKey="Van Broeckhoven C" first="Christine" last="Van Broeckhoven">Christine Van Broeckhoven</name></country><country name="Irlande (pays)"><noRegion><name sortKey="Gill, Michael" sort="Gill, Michael" uniqKey="Gill M" first="Michael" last="Gill">Michael Gill</name></noRegion></country><country name="Suède"><region name="Svealand"><name sortKey="Keller, Lina" sort="Keller, Lina" uniqKey="Keller L" first="Lina" last="Keller">Lina Keller</name></region><name sortKey="Fratiglioni, Laura" sort="Fratiglioni, Laura" uniqKey="Fratiglioni L" first="Laura" last="Fratiglioni">Laura Fratiglioni</name><name sortKey="Fratiglioni, Laura" sort="Fratiglioni, Laura" uniqKey="Fratiglioni L" first="Laura" last="Fratiglioni">Laura Fratiglioni</name><name sortKey="Graff, Caroline" sort="Graff, Caroline" uniqKey="Graff C" first="Caroline" last="Graff">Caroline Graff</name><name sortKey="Ingelsson, Martin" sort="Ingelsson, Martin" uniqKey="Ingelsson M" first="Martin" last="Ingelsson">Martin Ingelsson</name><name sortKey="Lannfelt, Lars" sort="Lannfelt, Lars" uniqKey="Lannfelt L" first="Lars" last="Lannfelt">Lars Lannfelt</name></country><country name="Canada"><region name="Ontario"><name sortKey="Rogaeva, Ekaterina" sort="Rogaeva, Ekaterina" uniqKey="Rogaeva E" first="Ekaterina" last="Rogaeva">Ekaterina Rogaeva</name></region><name sortKey="Lathrop, Mark" sort="Lathrop, Mark" uniqKey="Lathrop M" first="Mark" last="Lathrop">Mark Lathrop</name><name sortKey="St George Hyslop, Peter" sort="St George Hyslop, Peter" uniqKey="St George Hyslop P" first="Peter" last="St George-Hyslop">Peter St George-Hyslop</name></country><country name="Grèce"><noRegion><name sortKey="Tsolaki, Magda" sort="Tsolaki, Magda" uniqKey="Tsolaki M" first="Magda" last="Tsolaki">Magda Tsolaki</name></noRegion></country><country name="Italie"><region name="Latium"><name sortKey="Bossu, Paola" sort="Bossu, Paola" uniqKey="Bossu P" first="Paola" last="Bossù">Paola Bossù</name></region><name sortKey="Bosco, Paolo" sort="Bosco, Paolo" uniqKey="Bosco P" first="Paolo" last="Bosco">Paolo Bosco</name><name sortKey="Caffarra, Paolo" sort="Caffarra, Paolo" uniqKey="Caffarra P" first="Paolo" last="Caffarra">Paolo Caffarra</name><name sortKey="Caffarra, Paolo" sort="Caffarra, Paolo" uniqKey="Caffarra P" first="Paolo" last="Caffarra">Paolo Caffarra</name><name sortKey="Galimberti, Daniela" sort="Galimberti, Daniela" uniqKey="Galimberti D" first="Daniela" last="Galimberti">Daniela Galimberti</name><name sortKey="Mancuso, Michelangelo" sort="Mancuso, Michelangelo" uniqKey="Mancuso M" first="Michelangelo" last="Mancuso">Michelangelo Mancuso</name><name sortKey="Mecocci, Patrizia" sort="Mecocci, Patrizia" uniqKey="Mecocci P" first="Patrizia" last="Mecocci">Patrizia Mecocci</name><name sortKey="Nacmias, Benedetta" sort="Nacmias, Benedetta" uniqKey="Nacmias B" first="Benedetta" last="Nacmias">Benedetta Nacmias</name><name sortKey="Nacmias, Benedetta" sort="Nacmias, Benedetta" uniqKey="Nacmias B" first="Benedetta" last="Nacmias">Benedetta Nacmias</name><name sortKey="Panza, Francesco" sort="Panza, Francesco" uniqKey="Panza F" first="Francesco" last="Panza">Francesco Panza</name><name sortKey="Pilotto, Alberto" sort="Pilotto, Alberto" uniqKey="Pilotto A" first="Alberto" last="Pilotto">Alberto Pilotto</name><name sortKey="Sorbi, Sandro" sort="Sorbi, Sandro" uniqKey="Sorbi S" first="Sandro" last="Sorbi">Sandro Sorbi</name><name sortKey="Sorbi, Sandro" sort="Sorbi, Sandro" uniqKey="Sorbi S" first="Sandro" last="Sorbi">Sandro Sorbi</name><name sortKey="Spalletta, Gianfranco" sort="Spalletta, Gianfranco" uniqKey="Spalletta G" first="Gianfranco" last="Spalletta">Gianfranco Spalletta</name><name sortKey="Zompo, Maria Del" sort="Zompo, Maria Del" uniqKey="Zompo M" first="Maria Del" last="Zompo">Maria Del Zompo</name></country><country name="Finlande"><noRegion><name sortKey="Soininen, Hilkka" sort="Soininen, Hilkka" uniqKey="Soininen H" first="Hilkka" last="Soininen">Hilkka Soininen</name></noRegion><name sortKey="Hiltunen, Mikko" sort="Hiltunen, Mikko" uniqKey="Hiltunen M" first="Mikko" last="Hiltunen">Mikko Hiltunen</name><name sortKey="Hiltunen, Mikko" sort="Hiltunen, Mikko" uniqKey="Hiltunen M" first="Mikko" last="Hiltunen">Mikko Hiltunen</name><name sortKey="Soininen, Hilkka" sort="Soininen, Hilkka" uniqKey="Soininen H" first="Hilkka" last="Soininen">Hilkka Soininen</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000D36 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000D36 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Canada
|area= ParkinsonCanadaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:3896259
|texte= Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer’s disease
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:24162737" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a ParkinsonCanadaV1
| This area was generated with Dilib version V0.6.29. |  |